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Pregnancy and childbirth have a lasting effect on the mother's brain
Pregnancy and childbirth have profound, often long-lasting effects on brain physiology, mood, and behavior. New findings on the neurobiology of the maternal experience were presented at Neuroscience 2022, the annual meeting of the Society for Neuroscience and the world's largest source of new brain science and health news. Maternal mental illness is one of the most common complications during pregnancy and childbirth. Of the approximately 3.5 million people who give birth each year in the United States, about 20% will be affected by mental illnesses such as depression and anxiety. If left untreated, these diseases can have long-term negative effects on parents, babies, families...
Pregnancy and childbirth have a lasting effect on the mother's brain
Pregnancy and childbirth have profound, often long-lasting effects on brain physiology, mood, and behavior. New findings on the neurobiology of the maternal experience were presented at Neuroscience 2022, the annual meeting of the Society for Neuroscience and the world's largest source of new brain science and health news.
Maternal mental illness is one of the most common complications during pregnancy and childbirth. Of the approximately 3.5 million people who give birth each year in the United States, about 20% will be affected by mental illnesses such as depression and anxiety. If left untreated, these diseases can have long-term negative effects on parents, babies, families and society. Research into brain changes associated with maternal experiences is beginning to uncover the neural mechanisms underlying adaptive changes and perinatal mental illness.
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Today's new findings show that:
- Die Anfälligkeit oder Resilienz gegenüber postpartaler Depression in einem Nagetiermodell ist mit Veränderungen von Neuroimmunmarkern und Hormonen verbunden, die als Risiko-Biomarker oder mögliche therapeutische Ziele für die Erkrankung dienen könnten. (Janace Gifford, Universität von Delaware)
- Faktoren, die die Genexpression in Lern- und Gedächtnisnetzwerken regulieren, könnten Langzeiteffekte der mütterlichen Erfahrung im Gehirn von Mäusen vermitteln. (Ian S. Maze, Icahn School of Medicine am Berg Sinai)
- Die langanhaltenden antidepressiven Wirkungen von Allopregnanolon bei postpartaler Depression können auf Auswirkungen auf die Koordination von Aktivitäten in verschiedenen Gehirnregionen zurückzuführen sein, die an der Stimmung beteiligt sind. (Jamie Maguire, Medizinische Fakultät der Tufts-Universität)
“The neuroscientific findings presented today touch on various aspects of the transition to motherhood at multiple levels of inquiry and in different brain areas,” says session moderator Jodi Pawluski, a neuroscientist and psychotherapist whose research is affiliated with the Université de Rennes 1 and who studies how motherhood changes the brain. “These studies of the maternal brain provide important insights into the neuroscience of parenting and have implications for the management and management of perinatal mental illness.”
This research was supported by national funding agencies including the National Institutes of Health and private funding organizations. Learn more about maternal experiences and the brain at BrainFacts.org.
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