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Exposure to higher levels of air pollution linked to risk of chronic kidney disease
Both genetic and environmental factors contribute to chronic kidney disease (CKD). New research evaluated the interaction of air pollution and genetic factors in the development of CKD. The research will be presented at ASN Kidney Week 2022, November 3-6. Investigators analyzed data from 350,994 participants without CKD at baseline in the UK Biobank. Exposure to higher concentrations of air pollution components was associated with a higher risk of developing CKD. Compared to people with a high genetic risk of developing CKD, people with high exposure to air pollution and low...
Exposure to higher levels of air pollution linked to risk of chronic kidney disease
Both genetic and environmental factors contribute to chronic kidney disease (CKD). New research evaluated the interaction of air pollution and genetic factors in the development of CKD. The research will be presented at ASN Kidney Week 2022, November 3-6.
Investigators analyzed data from 350,994 participants without CKD at baseline in the UK Biobank. Exposure to higher concentrations of air pollution components was associated with a higher risk of developing CKD. Compared to people with a high genetic risk of developing CKD, people with high exposure to air pollution and a low genetic risk were at higher risk of developing CKD.
“Long-term exposure to air pollution may increase the risk of CKD, particularly in individuals at low genetic risk,” the authors write.
Study: “Air pollution, genetic factors and the risk of chronic kidney disease: a prospective study analyzing the polygenic risk score in the UK Biobank”
Source:
American Society of Nephrology
.