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A biodegradable, elastic plaster for the treatment of congenital diaphragmatic hernias
A University of Texas at Arlington biotechnology researcher is leading a team to develop a biodegradable, elastic patch as a new treatment for congenital diaphragmatic hernia (CDH). One in three newborns with this devastating condition dies. Five children are born with this birth defect every day in the United States. Yi Hong, a professor in the Department of Bioengineering, works with Aijun Wang and Dr. Diana L. Farmer of the University of California-Davis and Jun Liao, an associate professor of bioengineering at UT Arlington, to the highly competitive National Institutes of Health grant. We build something that gives and takes and with which...
A biodegradable, elastic plaster for the treatment of congenital diaphragmatic hernias
A University of Texas at Arlington biotechnology researcher is leading a team to develop a biodegradable, elastic patch as a new treatment for congenital diaphragmatic hernia (CDH).
One in three newborns with this devastating condition dies. Five children are born with this birth defect every day in the United States.
Yi Hong, a professor in the Department of Bioengineering, works with Aijun Wang and Dr. Diana L. Farmer of the University of California-Davis and Jun Liao, an associate professor of bioengineering at UT Arlington, to the highly competitive National Institutes of Health grant.
We build something that gives and takes and grows with the child. CDH is a serious birth defect characterized by incomplete development of the diaphragm.”
Yi Hong, Professor, Department of Bioengineering, University of Texas at Arlington
Hong said CDH can allow the stomach and intestines to move into the chest cavity, compressing the lungs and affecting development. Surgery can sometimes repair the defect; otherwise a prosthetic plaster must be used as a bridge. These patches are usually made of synthetic, biologically inactive materials such as Gore-Tex.
“Once this is done, these spots will not grow with the child,” Hong said. “In addition, the child often suffers another hernia, so developing a biodegradable, more natural solution is critical to the survival of these children.”
Michael Cho, professor and chair of the UTA Department of Bioengineering, said this could be life-saving research.
"Dr. Hong's research can help so many patients," Cho said. "Taking the research from our laboratories and using it in the medical field with partners is what makes UTA's research so personal and so important to what this university represents. It also represents the department's goal of advancing translational and transformative research."
Source:
University of Texas at Arlington
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