Study shows significant increase in recreational ketamine use among adults
A recent study that analyzed data from the National Survey on Drug Use and Health (NSDUH) found that past-year recreational use of ketamine among adults has increased dramatically since 2015, including significant shifts related to depression and sociodemographic characteristics such as race, age, and education status. The use of ketamine has shown promise in clinical trials for the treatment of various mental health conditions, including treatment-resistant depression, and the new research suggests that continued monitoring of trends in recreational use is critical to weigh these clinical benefits against the risks of unmonitored recreational use. To the …
Study shows significant increase in recreational ketamine use among adults
A recent study that analyzed data from the National Survey on Drug Use and Health (NSDUH) found that past-year recreational use of ketamine among adults has increased dramatically since 2015, including significant shifts related to depression and sociodemographic characteristics such as race, age, and education status. The use of ketamine has shown promise in clinical trials for the treatment of various mental health conditions, including treatment-resistant depression, and the new research suggests that continued monitoring of trends in recreational use is critical to weigh these clinical benefits against the risks of unmonitored recreational use.
Key findings include:
- Insgesamt stieg der Freizeitkonsum von Ketamin im vergangenen Jahr von 2015 bis 2019 um 81,8 % und von 2021 bis 2022 um 40 %.
- Bei Erwachsenen mit Depressionen war die Wahrscheinlichkeit, im vergangenen Jahr (2015–2019) Ketamin konsumiert zu haben, um 80 % höher, dieser Zusammenhang schwächte sich jedoch in späteren Jahren ab. Im Zeitraum 2021–2022 nahm der Ketaminkonsum nur bei Personen ohne Depression zu.
- Im Zeitraum 2021–2022 war die Wahrscheinlichkeit, dass Erwachsene im Alter von 26–34 Jahren im vergangenen Jahr Ketamin konsumiert hatten, um 66 % höher als bei Erwachsenen im Alter von 18–25 Jahren. Bei Personen mit Hochschulabschluss war die Wahrscheinlichkeit, Ketamin konsumiert zu haben, mehr als doppelt so hoch wie bei Personen mit Hochschulabschluss oder weniger.
- Menschen konsumierten eher Ketamin, wenn sie andere Substanzen wie Ecstasy/MDMA, GHB und Kokain konsumierten.
The researchers recommend expanding prevention work to settings such as colleges where younger adults may be at increased risk and providing education about the harms of polydrug use, particularly when combined with opioids. As medical ketamine becomes increasingly available, they also emphasize the need for continued monitoring of recreational ketamine use patterns and further research to understand the factors that contribute to ketamine use.
The study, published online in theJournal of Affective Disorderswas led by Kevin Yang, MD, a third-year resident in the Department of Psychiatry at UC San Diego School of Medicine. The research was supported by the National Institute on Drug Abuse of the National Institutes of Health.
Sources:
Yang, K.H.,et al. (2024). Trends and characteristics in ketamine use among US adults with and without depression, 2015–2022. Journal of Affective Disorders. doi.org/10.1016/j.jad.2024.12.108.