Higher maternal selenium associated with lower risk of strep throat in children

Higher maternal selenium associated with lower risk of strep throat in children

Higher maternal selenium levels during pregnancy were associated with a lower risk of streptococcal infections in children, suggesting a possible protective effect.

Scientists at Hokkaido University have found that exposure to certain metals and trace elements during pregnancy increases a child's risk of developing streptococcal infectionsPLOS one. These infections are common in children, especially those caused by group A streptococcus, a bacteria that commonly causes illnesses such as strep throat, skin infections and, in severe cases, more serious complications such as scarlet fever or invasive disease. The results could contribute to improved strategies to prevent childhood infections.

The research team followed more than 74,000 mothers and their children from a nationwide study in Japan. They measured the mothers' blood levels of various metals and trace elements, including selenium, mercury, cadmium, lead and manganese. The researchers then followed the children to see if they developed strep infections between the ages of three and four. Statistical analysis was used to examine potential associations between metal from mothers and risk of infection in children.

We found that mothers with higher selenium levels during pregnancy were less likely to have children who developed strep infections. This association was strongest among mothers with the highest blood selenium levels. However, high selenium concentrations during pregnancy can cause toxicity and adverse effects, so caution is necessary. Because this research is based on a single blood sample from pregnant mothers and the results of this study alone should not be used to recommend selenium intake during pregnancy. “

Hiroyoshi Iwata, first author of the study, Center for Environmental and Health Sciences, Hokkaido University

Selenium is a trace mineral that plays a key role in immune function, and previous studies have suggested that it may help the body fight infections by strengthening the immune system. These new findings support the idea that adequate selenium levels during pregnancy could help improve a child's immune defenses against bacterial infections.

This study supports the importance of adequate selenium intake during pregnancy for the long-term health of children and adds to a growing body of evidence suggesting that selenium plays an important role in immunity. However, this study specifically analyzed the relationship between maternal selenium levels and Streptococcus infections and did not evaluate relationships with other infectious diseases. Further research is needed to fully understand how selenium supports the immune system and to determine optimal levels during pregnancy.

Sources: