Amino acids in dextrose (intravenous)

Amino acids in dextrose (intravenous)

Amino acids in dextrose (intravenous)

Use for amino acids in dextrose

This medicine should only be given by or under your doctor's supervision.

Before using amino acids in dextrose

When deciding whether to use a medicine, the risks of taking the medicine must be weighed against the benefits it produces. This is a decision that you and your doctor will make. The following should be noted with this medicine:

Allergies

Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also tell your doctor if you have other allergies, such as to foods, dyes, preservatives or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatrics

Related studies conducted to date have not demonstrated any pediatric problems that would limit the benefit of amino acids with dextrose injection in the pediatric population. However, infants and children receiving this medicine are more likely to have serious adverse effects (including low or high blood sugar, aluminum toxicity, liver problems, or excess ammonia in the blood). Safety and effectiveness have not been established.

geriatrics

Related studies conducted to date have not shown any geriatric-specific problems that would limit the benefit of amino acids with dextrose injection in the elderly. However, older patients are at higher risk of age-related liver, kidney, or heart problems, which may require caution and dose adjustment in patients receiving this drug.

Breastfeeding

There are insufficient studies in women to determine the risk to infants when using this drug while breast-feeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug interactions

Although certain medicines should not be used together at all, in other cases two different medicines can be used together, although interactions may occur. In these cases, your doctor may want to change the dose or other precautions may be necessary. Tell your doctor if you are taking other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be taken during or near food or consumption of certain foods because interactions may occur. Consuming alcohol or tobacco with certain medications can also lead to interactions. Discuss using your medicine with food, alcohol or tobacco with your doctor.

Other medical problems

The presence of other medical problems may affect the use of this medicine. Be sure to tell your doctor if you have any other medical problems, especially:

• Azidose (zu viel Säure im Blut) oder
• Fehler im Aminosäurestoffwechsel, angeborene oder
• Lungenödem (Flüssigkeit in der Lunge) – Sollte bei Patienten mit diesen Erkrankungen nicht angewendet werden.

• Diabetes bzw
• Herzkrankheit bzw
• Nierenerkrankung – Mit Vorsicht verwenden. Kann diese Bedingungen verschlimmern.

• Elektrolytungleichgewicht bzw
• Schwere Stoffwechselstörungen – sollten vor der Anwendung dieses Arzneimittels behoben werden.

• Hyperglykämie (hoher Blutzucker), verschlimmert durch Dextrose oder
• Geschwächtes Immunsystem, verursacht durch schlechte Ernährung oder andere Medikamente – kann das Infektionsrisiko erhöhen.

• Bei stark unterernährten Patienten kann es zu einem Refeeding-Syndrom kommen. Überwachen und steigern Sie die Nährstoffaufnahme der Patienten langsam.

Proper use of amino acids in dextrose

A nurse or other trained health professional will give you this medicine in a hospital or clinic. It is given through a needle inserted into one of your veins.

Precautions when using amino acids in dextrose

It is very important that your doctor checks you or your child closely to make sure this medicine is working properly. Blood and urine tests are required to determine adverse effects.

This medicine may increase your risk of blood clots forming in the lungs or veins. This can be life-threatening and requires immediate medical attention. Contact your doctor immediately if you experience cough, chest pain, fast heartbeat, difficulty breathing, dizziness, lightheadedness or fainting or tenderness, pain, swelling, feeling warm, skin discoloration, and protruding superficial veins in the affected area.

Serious allergic reactions may occur while using this medication. Tell your doctor right away if you have the following symptoms: rapid, shallow breathing, difficulty breathing, fast heartbeat, lightheadedness, dizziness or fainting, nausea or vomiting, rash or itchy skin, or fever or chills.

This medicine may increase your risk of developing infections. Call your doctor immediately if you experience persistent cough, weight loss, night sweats, fever, chills, flu-like symptoms (such as a runny or stuffy nose, headache, blurred vision, or generally feeling unwell), painful or difficult urination, or sores, ulcers, or white patches in the mouth or lips.

This medicine may affect your blood sugar levels. Contact your doctor immediately if you become more thirsty or urinate more frequently. If you notice a change in the results of your urine or blood sugar test or have any questions, contact your doctor.

Call your doctor if you notice redness, swelling, pain, or infection at the injection site.

This medicine can cause liver problems, including parenteral nutrition-related liver disease (PNALD). This usually occurs in patients who have been on parenteral nutrition for a long period of time, especially in premature infants. Contact your doctor immediately if you have pain or tenderness in your upper abdomen, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin.

This medicine can cause electrolyte imbalance, fluid overload, and aluminum toxicity (too much aluminum in the blood). Talk to your doctor if you have concerns.

Side effects of amino acids in dextrose

In addition to the necessary effects, a medicine may also have some undesirable effects. Although not all of these side effects may occur, medical attention may be required if they occur.

Contact your doctor or nurse immediately if any of the following side effects occur:

Incident not known

• Angst
• Blähungen
• verschwommene Sicht
• Brustschmerzen
• Schüttelfrost
• Verwirrung
• Husten oder Heiserkeit
• dunkler Urin
• Abnahme der Urinmenge
• Schwindel oder Benommenheit
• trockener Mund
• extremer Durst
• Ohnmacht
• schneller Herzschlag
• Ermüdung
• Fieber
• gerötete, trockene Haut
• Fruchtartiger Atemgeruch
• erhöhter Hunger
• Erhöhter Durst
• vermehrtes Wasserlassen
• heller Stuhlgang
• Schmerzen im unteren Rücken oder an der Seite
• Brechreiz
• lautes, rasselndes Atmen
• Schmerzen oder Rötung an der Injektionsstelle
• schmerzhaftes oder schwieriges Wasserlassen
• blasse Haut an der Injektionsstelle
• Beschlagnahme
• Magenschmerzen
• Zucker im Urin
• Schwitzen
• Schwellung der Finger, Hände, Füße oder Unterschenkel
• Druckempfindlichkeit, Schmerzen, Schwellung, Wärme, Hautverfärbung und hervorstehende oberflächliche Venen im betroffenen Bereich
• Atembeschwerden
• Atembeschwerden in Ruhe
• unerklärlicher Gewichtsverlust
• große oder sehr kleine Mengen urinieren
• Erbrechen
• Schwäche
• Gewichtszunahme
• gelbe Augen oder Haut

Some patients may also experience other side effects not listed. If you notice other side effects, contact your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Commonly used brand names

In the USA

• Clinimix

Available dosage forms:

• Lösung

Therapeutic Class: Parenteral Amino Acids

Chemical Class: Amino Acid

More information