Chlordiazepoxide hydrochloride (oral)

Chlordiazepoxide hydrochloride (oral)

Uses for Chlordiazepoxide Hydrochloride

Chlordiazepoxide is a benzodiazepine. Benzodiazepines belong to a group of drugs called central nervous system (CNS) depressants. These are medicines that slow down the nervous system.

This medicine is only available with a doctor's prescription.

Before using chlordiazepoxide hydrochloride

When deciding whether to use a medicine, the risks of taking the medicine must be weighed against the benefits it produces. This is a decision that you and your doctor will make. The following should be noted with this medicine:

Allergies

Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also tell your doctor if you have other allergies, such as to foods, dyes, preservatives or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatrics

No appropriate studies have been conducted on the relationship between age and the effects of chlordiazepoxide in children younger than 6 years. Safety and effectiveness have not been established.

geriatrics

Studies conducted to date have not shown any geriatric-specific problems that would limit the benefit of chlordiazepoxide in the elderly. However, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness are more common in older people, who tend to be more sensitive to the effects of chlordiazepoxide than younger adults. Elderly patients may require a lower dose to reduce adverse effects.

Breastfeeding

There are insufficient studies in women to determine the risk to infants when using this drug while breast-feeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug interactions

Although certain medicines should not be used together at all, in other cases two different medicines can be used together, although interactions may occur. In these cases, your doctor may want to change the dose or other precautions may be necessary. If you are taking this medicine, it is particularly important that your doctor knows whether you are taking any of the medicines listed below. The following interactions were selected for their potential significance and are not necessarily exhaustive.

The use of this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or to change some of the other medications you are taking.

• Flumazenil

Using this medicine with any of the following medicines is not usually recommended but may be necessary in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both medicines.

• Alfentanil
• Alprazolam
• Amobarbital
• Aripiprazol
• Benzhydrocodon
• Bromazepam
• Bromoprid
• Buprenorphin
• Butabarbital
• Butalbital
• Butorphanol
• Calciumoxybat
• Cannabidiol
• Cannabis
• Carbinoxamin
• Carisoprodol
• Cetirizin
• Chloralhydrat
• Chlorzoxazon
• Clobazam
• Clonazepam
• Kodein
• Dantrolen
• Daridorexant
• Dexmedetomidin
• Dihydrocodein
• Doxylamin
• Esketamin
• Ethchlorvinyl
• Fentanyl
• Flibanserin
• Fospropofol
• Gabapentin
• Gabapentin Enacarbil
• Hydrocodon
• Hydromorphon
• Ivacaftor
• Ketamin
• Lacosamid
• Lemborexant
• Levocetirizin
• Levorphanol
• Lofexidin
• Loxapin
• Magnesiumoxybat
• Meclizin
• Meperidin
• Mephenesin
• Mephobarbital
• Meprobamat
• Metaxalone
• Methadon
• Methocarbamol
• Methohexital
• Metoclopramid
• Midazolam
• Mirtazapin
• Morphium
• Morphinsulfat-Liposom
• Nalbuphin
• Olanzapin
• Oxycodon
• Oxymorphon
• Pentazocin
• Pentobarbital
• Periciazin
• Phenobarbital
• Kaliumoxybat
• Pregabalin
• Primidon
• Propofol
• Remimazolam
• Ropeginterferon Alfa-2b-njft
• Scopolamin
• Secobarbital
• Natriumoxybat
• Sufentanil
• Tapentadol
• Thiopental
• Topiramat
• Tramadol
• Trazodon
• Zolpidem
• Zuranolon

Using this medicine with any of the following medicines may result in an increased risk of certain side effects, but using both medicines may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both medicines.

• Ketoconazol
• Rifapentin
• Johanniskraut
• Theophyllin

Interactions with food/tobacco/alcohol

Certain medicines should not be taken during or near food or consumption of certain foods because interactions may occur. Consuming alcohol or tobacco with certain medications can also lead to interactions. The following interactions were selected for their potential significance and are not necessarily exhaustive.

Using this medicine with any of the following medicines may result in an increased risk of certain side effects, but may be unavoidable in some cases. If used together, your doctor may change the dose or frequency of use of this medication, or give you special instructions about food, alcohol, or tobacco consumption.

• Ethanol

Other medical problems

The presence of other medical problems may affect the use of this medicine. Be sure to tell your doctor if you have any other medical problems, especially:

• Nierenerkrankung bzw
• Lebererkrankung – Mit Vorsicht anwenden. Die Wirkung kann durch die langsamere Entfernung des Arzneimittels aus dem Körper verstärkt werden.

• Porphyrie (genetische Störung) – Mit Vorsicht anwenden. Kann diesen Zustand verschlimmern.

Proper use of chlordiazepoxide hydrochloride

Only take this medicine as directed by your doctor. Do not take more of it, do not take it more often, or take it for longer than your doctor prescribed.

dosage

The dose of this medicine is different for different patients. Follow your doctor's instructions or the label directions. The following information includes average doses of this medicine only. If your dose is different, do not change it unless your doctor tells you to.

The amount of medicine you take depends on the strength of the medicine. In addition, the number of doses you take each day, the time between doses, and how long you take the medicine depend on the medical problem for which you are using the medicine.

• Für orale Darreichungsform (Kapseln):
  • Bei Angst:
    • Erwachsene – 5 bis 25 Milligramm (mg) drei- oder viermal täglich.
    • Ältere Erwachsene – 5 Milligramm (mg) zwei- bis viermal täglich.
    • Kinder ab 6 Jahren: Zunächst 5 Milligramm (mg) zwei- bis viermal täglich. Ihr Arzt kann Ihre Dosis bei Bedarf erhöhen.
    • Kinder unter 6 Jahren: Anwendung und Dosierung müssen von Ihrem Arzt festgelegt werden.
  • Bei Befürchtungen und Ängsten vor einer Operation:
    • Erwachsene – 5 bis 10 Milligramm (mg) drei- oder viermal täglich, eingenommen mehrere Tage vor der Operation.
    • Kinder – Anwendung und Dosis müssen von Ihrem Arzt festgelegt werden.
  • Bei Symptomen eines Alkoholentzugs:
    • Erwachsene – zunächst 50 bis 100 Milligramm (mg). Die Dosis kann wiederholt werden, bis die Bewegung unter Kontrolle ist. Allerdings beträgt die Dosis in der Regel nicht mehr als 300 mg pro Tag.
    • Kinder – Anwendung und Dosis müssen von Ihrem Arzt festgelegt werden.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.

storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Protect from freezing.

Keep away from children.

Do not keep medications that are outdated or no longer needed.

Ask your doctor how to throw away medicines you don't use.

Precautions when using chlordiazepoxide hydrochloride

It is very important that your doctor checks you or your child's progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for adverse effects.

Using this medicine during pregnancy may harm your unborn baby. Use an effective form of birth control to prevent pregnancy. If you think you have become pregnant while using this medicine, tell your doctor immediately.

This medicine may make some people, especially older people, feel sleepy, dizzy, light-headed, clumsy or unsteady, or less alert than they normally are. Make sure you know how you react to this medicine before driving, operating machinery, or doing other activities that could be dangerous if you are not alert or unable to think or see well.

This medicine increases the effects of alcohol and other central nervous system (CNS) depressants. CNS depressants are medicines that slow down the nervous system, which may cause drowsiness or make you less alert. Some examples of CNS depressants include antihistamines or medications for hay fever, allergies, or colds; sedatives, sedatives or sleeping pills; prescription painkillers or narcotics; barbiturates (used to treat seizures); muscle relaxants; or anesthetics (numbing medicines), including some dental anesthetics. This effect may last for a few days after you stop taking this medicine. Consult your doctor before taking any of the above medicines while using this medicine.

If you develop any unusual and strange thoughts or behavior while taking chlordiazepoxide, be sure to discuss this with your doctor. Some changes that have occurred in people taking this medicine are similar to those seen in people who drink alcohol and then behave in ways that are not normal. Other changes may be more unusual and extreme, such as confusion, worsening depression, hallucinations (seeing, hearing, or feeling things that are not there), suicidal thoughts, and unusual agitation, nervousness, or irritability.

Do not stop taking it without first consulting your doctor. Your doctor may want you to gradually reduce the amount you take before stopping it completely. This can help prevent your condition from worsening and reduce the possibility of withdrawal symptoms such as convulsions (seizures), stomach or muscle cramps, tremors, or unusual behavior.

This medicine is for short-term use only (usually 7 to 10 days). If your condition does not improve or worsens, contact your doctor.

Side effects of chlordiazepoxide hydrochloride

In addition to the necessary effects, a medicine may also have some undesirable effects. Although not all of these side effects may occur, medical attention may be required if they occur.

Consult your doctor immediately if any of the following side effects occur:

Rarely

• Ohnmacht
• Stimmungsschwankungen oder mentale Veränderungen
• Zittern und unsicherer Gang
• Unsicherheit, Zittern oder andere Probleme mit der Muskelkontrolle oder -koordination

Incident not known

• Bauch- und Muskelkrämpfe
• Schüttelfrost
• lehmfarbener Stuhlgang
• Krämpfe
• Husten oder Heiserkeit
• dunkler Urin
• Schwierigkeiten beim Sprechen
• Schwindel
• sabbern
• Fieber mit oder ohne Schüttelfrost
• allgemeines Gefühl von Müdigkeit oder Schwäche
• Kopfschmerzen
• Juckreiz
• heller Stuhlgang
• Appetitverlust
• Verlust der Gleichgewichtskontrolle
• Schmerzen im unteren Rücken oder an der Seite
• Muskelzittern, -zuckungen oder -steifheit
• Übelkeit und Erbrechen
• schmerzhaftes oder schwieriges Wasserlassen
• blasse Haut
• Ausschlag
• Unruhe
• Zittern in den Beinen, Armen, Händen oder Füßen
• schlurfender Gang
• Schlaflosigkeit
• Halsentzündung
• Wunden, Geschwüre oder weiße Flecken auf den Lippen oder im Mund
• Steifheit der Gliedmaßen
• Magenschmerzen
• Schwitzen
• Schwellung
• Schlafstörungen
• Drehbewegungen des Körpers
• nicht schlafen können
• unkontrollierte Bewegungen, insbesondere von Gesicht, Hals und Rücken
• unangenehmer Atemgeruch
• ungewöhnliche Blutergüsse oder Blutungen
• ungewöhnliche Müdigkeit oder Schwäche
• Erbrechen von Blut
• gelbe Augen oder Haut

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Bewusstseinsveränderung
• Mangel an Koordination
• Bewusstlosigkeit
• Schläfrigkeit oder ungewöhnliche Schläfrigkeit

Some side effects may occur that usually do not require medical attention. These side effects may disappear during treatment as your body gets used to the medicine. Your doctor may also be able to give you ways to prevent or reduce some of these side effects. If any of the following side effects persist or are bothersome, or if you have any questions, contact your doctor:

Incident not known

• Vermindertes Interesse am Geschlechtsverkehr
• Schwierigkeiten beim Stuhlgang (Stuhl)
• Unfähigkeit, eine Erektion zu haben oder aufrechtzuerhalten
• Steigerung der sexuellen Fähigkeiten, des Verlangens, des Antriebs oder der Leistung
• erhöhtes Interesse am Geschlechtsverkehr
• Verlust der sexuellen Fähigkeiten, des Verlangens, des Antriebs oder der Leistung
• Menstruationsveränderungen
• Hautblasen

Some patients may also experience other side effects not listed. If you notice other side effects, contact your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Commonly used brand names

In the USA

• Librium

Available dosage forms:

• Kapsel

Therapeutic class: anti-anxiety

Pharmacological class: Chlordiazepoxide

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