Doxycycline (subgingival)

Doxycycline (subgingival)

Doxycycline (subgingival)

Uses for Doxycycline

Doxycycline is used to treat periodontitis (a disease of the gums). Periodontitis is caused by bacteria that grow below the gum line. Doxycycline works by preventing bacterial growth. Reducing the amount of bacteria helps reduce inflammation and swelling in the mouth and bleeding around the teeth. Doxycycline is placed into deep gum pockets next to your teeth to reduce the depth of the pockets.

Before using doxycycline

When deciding whether to use a medicine, the risks of taking the medicine must be weighed against the benefits it produces. This is a decision that you and your doctor will make. The following should be noted with this medicine:

Allergies

Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also tell your doctor if you have other allergies, such as to foods, dyes, preservatives or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatrics

Use in infants and children under 8 years of age is not recommended. Tetracyclines such as doxycycline can cause permanent tooth discoloration and slow bone growth. The safety and effectiveness of doxycycline in children 8 years and older have not been established.

geriatrics

There is no information available on the relationship between age and the effects of doxycycline in geriatric patients.

Breastfeeding

There are insufficient studies in women to determine the risk to infants when using this drug while breast-feeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug interactions

Although certain medicines should not be used together at all, in other cases two different medicines can be used together, although interactions may occur. In these cases, your doctor may want to change the dose or other precautions may be necessary. If you are receiving this medicine, it is particularly important that your doctor knows whether you are taking any of the medicines listed below. The following interactions were selected for their potential significance and are not necessarily exhaustive.

The use of this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or to change some of the other medications you are taking.

• Acitretin

Using this medicine with any of the following medicines is not usually recommended but may be necessary in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both medicines.

• Amoxicillin
• Ampicillin
• Askorbinsäure
• Bacampicillin
• Bexaroten
• Cholera-Impfstoff, lebend
• Cloxacillin
• Desogestrel
• Dicloxacillin
• Dienogest
• Drospirenon
• Östradiol
• Ethinylestradiol
• Ethynodiol
• Etretinat
• Gestoden
• Isotretinoin
• Levonorgestrel
• Magnesiumsulfat
• Mestranol
• Methicillin
• Methotrexat
• Methoxyfluran
• Nafcillin
• Nomegestrol
• Norethindron
• Norgestimate
• Norgestrel
• Oxacillin
• Palovaroten
• Penicillin G
• Penicillin G Benzathin
• Penicillin G Procain
• Penicillin V
• Piperacillin
• Pivampicillin
• Porfimer
• Quizartinib
• Sultamicillin
• Temocillin
• Tretinoin

Using this medicine with any of the following medicines may result in an increased risk of certain side effects, but using both medicines may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both medicines.

• Aminolävulinsäure
• Rifampin
• Rifapentin

Interactions with food/tobacco/alcohol

Certain medicines should not be taken during or near food or consumption of certain foods because interactions may occur. Consuming alcohol or tobacco with certain medications can also lead to interactions. Discuss using your medicine with food, alcohol or tobacco with your doctor.

Other medical problems

The presence of other medical problems may affect the use of this medicine. Be sure to tell your doctor if you have any other medical problems, especially:

• Candidiasis (Hefepilzinfektion) im Mund oder in der Vorgeschichte: Mit Vorsicht anwenden. Kann diesen Zustand verschlimmern.

• Erkrankungen mit schweren parodontalen Defekten oder
• Zahnimplantate bzw
• Schwaches Immunsystem (verursacht durch Diabetes, HIV-Infektion oder Patienten, die Krebs oder Strahlenbehandlungen erhalten) – Atridox® wurde bei Patienten mit diesen Erkrankungen nicht getestet und bewertet.

Proper use of doxycycline

The doxycycline periodontal system is inserted by your dentist into one or more deep gum pockets next to your teeth. A dental cast or adhesive is placed over it to hold the system in place. The treatment can be repeated four months later.

The duration of treatment for the doxycycline periodontal system is seven days after placement by your dentist. If the system becomes loose or falls out before 7 days, contact your dentist.

The periodontal system with doxycycline does not need to be removed by the dentist; it will dissolve. The dental cast or adhesive that holds the system in place may fall out naturally. However, if the dental dressing or adhesive is still present after 7 days, it should be removed by the dentist.

After putting the medicine in your mouth, avoid any actions that could cause the medicine to leak out. For example:

• Putzen Sie nicht die Zähne, die 7 Tage lang behandelt wurden.
• Benutzen Sie 7 Tage nach der Behandlung keine Zahnseide oder andere Reinigungsutensilien, die in die Zahnzwischenräume gelangen.

Precautions when using doxycycline

It is very important that your dentist check your progress while you are receiving this medicine. Don't miss a dentist appointment.

Using this medicine during pregnancy (especially in the last half of pregnancy) may harm your unborn baby. Use an effective form of birth control to prevent pregnancy. If you think you have become pregnant while using this medicine, tell your doctor immediately.

If you experience pain, swelling, or other problems in the treated areas, contact your dentist as soon as possible.

Oral contraceptives (birth control pills) that contain estrogen may not work properly if you take them while treating the periodontal system with doxycycline. To prevent pregnancy, use another form of contraception (e.g., condoms, diaphragms, or contraceptive foams or jellies) while the periodontal system is intact with doxycycline. If you have any questions about this, contact your doctor.

Do not floss or brush treated teeth for 7 days after treatment with doxycycline. Brushing or flossing can cause the system to become loose or fall out.

Tetracyclines such as doxycycline can cause your skin to be more sensitive to sunlight than normal. Even short-term exposure to the sun can cause a rash, itching, redness or other discoloration of the skin, or severe sunburn. For a period of 7 days after administration of doxycycline to the periodontal system:

• Vermeiden Sie nach Möglichkeit direkte Sonneneinstrahlung, insbesondere zwischen 10:00 und 15:00 Uhr.
• Tragen Sie Schutzkleidung, einschließlich einer Kopfbedeckung. Tragen Sie außerdem eine Sonnenbrille.
• Tragen Sie ein Sonnenschutzprodukt mit einem Hautschutzfaktor (LSF) von mindestens 15 auf. Einige Patienten benötigen möglicherweise ein Produkt mit einem höheren Lichtschutzfaktor, insbesondere wenn sie einen hellen Teint haben. Wenn Sie diesbezüglich Fragen haben, wenden Sie sich an Ihren Arzt.
• Tragen Sie einen Sonnenschutz-Lippenstift mit einem Lichtschutzfaktor von mindestens 15 auf, um Ihre Lippen zu schützen.
• Benutzen Sie weder eine Sonnenlampe noch ein Solarium oder eine Solariumkabine.

After the 7-day periodontal system treatment period with doxycycline, you may continue to be sensitive to sunlight or sunlamps for 2 weeks to several months or longer. If you experience a severe reaction, contact your dentist or doctor.

Doxycycline side effects

In addition to the necessary effects, a medicine may also have some undesirable effects. Although not all of these side effects may occur, medical attention may be required if they occur.

Contact your doctor or nurse immediately if any of the following side effects occur:

Less common

• Bluthochdruck
• Lockerheit des Zahnes
• Zahn- oder Zahnfleischschmerzen (stark oder anhaltend)

Some side effects may occur that usually do not require medical attention. These side effects may disappear during treatment as your body gets used to the medicine. Your doctor may also be able to give you ways to prevent or reduce some of these side effects. If any of the following side effects persist or are bothersome, or if you have any questions, contact your doctor:

More common

• Erkältungsähnliche Symptome
• Zahnfleischbeschwerden, Schmerzen oder Schmerzen
• Kopfschmerzen
• Druckempfindlichkeit des Zahnes
• Zahnschmerzen

Less common

• Blähungen im Bauch oder Magen oder Beckenschmerzen
• Husten
• Durchfall
• Zahnfleischrötung
• Verdauungsstörungen, Magenbeschwerden oder Bauchschmerzen
• grippeähnliche Symptome
• Mundschmerzen oder Schmerzen
• Muskelkater
• Empfindlichkeit des Zahns gegenüber Hitze oder Kälte
• Kurzatmigkeit
• Schlaflosigkeit
• Halsentzündung
• verstopfter Kopf, postnasaler Tropfen oder verstopfte Nase

Some patients may also experience other side effects not listed. If you notice other side effects, contact your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Chemical Class: Tetracycline (Class)

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