Efficient

Efficient

What is efficient?

Effient is used in people who have had balloon angioplasty to open blocked arteries after a heart attack or severe chest pain.

Effient can help reduce the risk of another heart attack or stroke.

Warnings

You should not take Effient if you have active bleeding, such as a stomach ulcer or bleeding in the brain, if you have ever had a stroke or “mini-stroke,” or if you are scheduled to have surgery, especially heart bypass surgery.

Effient increases the risk of bleeding, which can be serious or life-threatening.Call your doctor or seek emergency medical attention if you have bleeding that doesn't stop, if you have black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds.

You may need to stop taking the medicine for a short time before surgery or dental treatment. Do not stop taking Effient unless your doctor tells you to.

Do not take NSAIDs (non-steroidal anti-inflammatory drugs) without your doctor's advice while you are taking Effient. NSAIDs include ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol). , mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), piroxicam (Feldene) and others.

Before you take this medicine

You should not use Effient if you are allergic to prasugrel or if you have:

• active bleeding, such as B. a stomach ulcer or bleeding in the brain (e.g. due to a head injury);

• a history of stroke, including TIA (“mini-stroke”); or

• if you are scheduled to have surgery, especially heart bypass surgery (coronary artery bypass grafting or CABG).

To make sure Effient is safe for you, tell your doctor if you have ever had:

• a stomach ulcer, colon polyps, or diverticulosis;

• bleeding problems;

• a surgery, injury or medical emergency;

• liver or kidney disease;

• if you are allergic to clopidogrel or ticlopidine;

• if you weigh less than 60 kilograms; or

• if you are also taking other medicines to treat or prevent blood clots.

Tell your doctor if you are pregnant or breastfeeding.

How should I take Effient?

Take Effient exactly as your doctor has told you. Follow all instructions on your prescription label and read any medication guides or instructions for use. If you are also taking aspirin, follow your doctor's instructions about how much to take and how long to take it.

Effiient can be taken with or without food.

Swallow the tablet whole and do not crush, chew or break it.

Because Effient prevents blood clotting,This medicine may also cause you to bleed more easily, even from a minor injury.Seek emergency medical attention if you have bleeding that doesn't stop.

Tell your doctor if you are scheduled to have surgery or dental treatment.

Do not stop using Effient without your doctor's advice, even if you feel well. Stopping this medicine too soon may increase your risk of a blood clot, heart attack, or death.

Store Effient at room temperature, away from moisture and heat. Store the tablets in their original container along with the package or canister containing the moisture-absorbing preservative.

Dosage information

Usual Effient Adult Dose for Acute Coronary Syndrome:

Starting dose: 60 mg once orally
Maintenance dose: 10 mg orally once daily

Comments:
-No clear benefit was observed when the loading dose of this drug was administered before diagnostic coronary angiography compared to the time of percutaneous coronary intervention (PCI); However, in patients undergoing PCI or early coronary artery bypass grafting (CABG), the risk of bleeding was increased with early administration.
-Aspirin 75 to 325 mg daily should be taken with this medication.

Use: To reduce the rate of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome (ACS) who are to be treated with PCI for unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI), or ST-segment elevation myocardial infarction (STEMI).

Usual Geriatric Dose of Effient for Acute Coronary Syndrome:

65 to under 75 years:
-Initial dose: 60 mg orally once
-Maintenance dose: 10 mg orally once daily

75 years of age or older: Use is generally not recommended in such patients except in high-risk situations (e.g., diabetes or previous myocardial infarction) when the benefit outweighs the risk.

Comments:
-No clear benefit was observed when the loading dose of this drug was administered before diagnostic coronary angiography compared to the time of percutaneous coronary intervention (PCI); However, in patients undergoing PCI or early coronary artery bypass grafting (CABG), the risk of bleeding was increased with early administration.
-Aspirin 75 to 325 mg daily should be taken with this medication.

Use: To reduce the rate of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome (ACS) who are to be treated with PCI for unstable angina (UA), non-ST-segment elevation myocardial infarction (NSTEMI), or ST-segment elevation myocardial infarction (STEMI).

What happens if I miss a dose?

Take the medicine as soon as possible, but skip the missed dose if it is almost time for the next dose. Do not take two doses at the same time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help hotline at 1-800-222-1222.

What should I avoid while taking Effient?

Avoid activities that could increase the risk of bleeding or injury. Be particularly careful when shaving or brushing your teeth.

Consult your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen, naproxen, Advil, Aleve, Motrin, and others. Using an NSAID with Effient may cause easy bruising or bleeding.

Efficient side effects

If necessary, get emergency medical helpSigns of an allergic reaction to Effient:hives; dizziness, chest pain, difficulty breathing; Swelling of your face, lips, tongue, or throat.

Prasugrel increases the risk of bleeding, which can be serious or life-threatening.

Call your doctor immediately if you have:

• a light-headed feeling, as if you were going to faint;

• any bleeding that doesn't stop;

• pink or brown urine;

• Signs of a serious blood clotting disorder- pale skin, purple spots under the skin or in the mouth, fever, fast heartbeat, weakness, stomach pain, difficulty breathing, jaundice (yellowing of the skin or eyes);

• Signs of stomach bleeding- bloody or tarry stools, coughing up blood, or vomit that looks like coffee grounds; or

• Signs of a stroke- sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance.

The risk of bleeding is higher in older adults.

Common side effects of Effient may include:

• nosebleeds; or

• easy bruising or bleeding.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Effient?

Tell your doctor about all other medicines you are taking, especially:

• opioid medications; or

• any other medicines used to treat or prevent blood clots, including heparin or warfarin (Coumadin, Jantoven).

This list is not complete. Other medications may interact with prasugrel, including prescription and over-the-counter medications, vitamins, and herbal products. Not all possible drug interactions are listed here.

• Welche Medikamente schließen eine Blut-/Plasmaspende aus?

More information

Remember to keep this and all other medicines out of the reach of children, never share your medicines with others, and only use Effient for the prescribed indication.