Fibrin glue for topical use

Fibrin glue for topical use

Fibrin glue for topical use

What is fibrin glue topical?

Topical fibrin glue is used to control bleeding during surgery when other methods of closing a wound or incision (e.g., sutures, tape, or heat) are not possible. A topical fibrin glue may also be used to prevent leakage from a wound in the stomach tissue after removal of a colostomy.

Topical fibrin glue is sometimes used to help stick skin tissue together during skin grafts or cosmetic surgery.

Topical fibrin glue may also be used for purposes not listed in this medication guide.

Topical side effects of fibrin sealants

If necessary, get emergency medical helpSigns of an allergic reaction: hives, itching, warmth, redness, numbness, tingling; nausea, vomiting, drowsiness, fast or slow heartbeat; Wheezing, chest tightness, difficulty breathing; Swelling of your face, lips, tongue, or throat.

Fibrin glue is sometimes applied with a sprayer that uses gas pressure. High pressure can cause air or gas to be released beneath the skin tissue, where it can then travel throughout the body. This may be more likely if a healthcare provider improperly uses high pressure settings during spray application of fibrin glue.Air or gases trapped in the body can have serious or life-threatening effects. Talk to your doctor about this risk.

Tell your caregivers immediately if you have:

• chest pain, cough, difficulty breathing, shortness of breath;

• confusion, agitation, panic, extreme fear;

• sudden numbness or weakness (especially on one side of the body);

• sudden severe headache, slurred speech, problems with vision or balance;

• blue appearance of your skin or lips;

• nausea, dizziness or feeling dizzy;

• a light-headed feeling, as if you were going to faint; or

• redness, itching, irritation, or slow healing of the skin wound or treated area;

Common side effects of topical fibrin glue may include:

• Itching; or

• Swelling or bruising.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to FDA at 1-800-FDA-1088.

Warnings

If you are allergic to cows or products made from cows, you should not have topical fibrin glue treated.

Before you take this medicine

If you are allergic to cows or products made from cows, you should not have topical fibrin glue treated.

It is not known whether topical use of fibrin glue will harm an unborn child. Tell your doctor if you are pregnant.

It is not known whether topical fibrin glue passes into breast milk or whether it could harm a breastfed baby. Tell your doctor if you are breastfeeding a baby.

How should I apply fibrin glue topically?

Topical fibrin glue can be sprayed or dripped onto the affected skin or surgical area. Topical fibrin glue is applied by healthcare professionals in a surgical or clinical setting.

Topical fibrin glue is made from human plasma (a portion of blood), which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk that it contains infectious agents. However, there is still a small possibility that it could transmit disease. Talk to your doctor about the risks and benefits of taking this medication.

Some people develop symptoms of a viral infection after being treated topically with fibrin glue.Call your doctor if you have flu-like symptomssuch as fever, chills, drowsiness or a runny nose. You may also experience joint pain and a rash about two weeks after your flu symptoms begin.

Information on topical dosage of fibrin glue

Usual adult dose to stop bleeding:

Before use, the wound surface should be as dry as possible.

Apply fibrin glue topically in a thin layer. The initial amount of product to be applied should be sufficient to fully cover the intended area of ​​application. If necessary, the application can be repeated.

The dose of topical fibrin glue required depends on the size of the surface to be covered.

After the two components have been applied, fix or hold the sealed parts in the desired position for at least three to five minutes to ensure that the topical fibrin glue adheres firmly to the surrounding tissue.

Usual adult dosage for closure of a colostomy:

Before use, the wound surface should be as dry as possible.

Apply fibrin glue topically in a thin layer. The initial amount of product to be applied should be sufficient to fully cover the intended area of ​​application. If necessary, the application can be repeated.

The dose of topical fibrin glue required depends on the size of the surface to be covered.

After the two components have been applied, fix or hold the sealed parts in the desired position for at least three to five minutes to ensure that the topical fibrin glue adheres firmly to the surrounding tissue.

What happens if I miss a dose?

Because you receive fibrin glue topically in the clinical setting, you are unlikely to miss a dose.

What happens if I overdose?

Because fibrin glue is applied topically by healthcare professionals in a medical setting, overdose is unlikely.

What should I avoid after topical fibrin glue treatment?

Follow your doctor's instructions regarding any food, drink, or activity restrictions.

What other medications will affect topical use of fibrin glue?

It is unlikely that other medications you take orally or inject will have an effect on fibrin glue applied topically. But many medications can interact with each other. Tell each of your healthcare providers about all medications you take, including prescription and over-the-counter medications, vitamins, and herbal products.

More information

Remember to keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the prescribed indication.