Locametz (intravenous)

Locametz (intravenous)

Locametz (intravenous)

Possible uses for Locametz

Gallium Ga 68 PSMA-11 Injection is used with a PET (positron emission tomography) scan of prostate-specific membrane antigen (PSMA)-positive lesions in men with prostate cancer. It is given to patients with suspected metastasis (cancer that has spread to other parts of the body) who are eligible for initial treatment and to patients with suspected recurrence (cancer that keeps coming back), based on an elevated serum prostate-specific antigen (PSA level) and for selection in patients with metastatic (spread) prostate cancer who have a PSMA-targeted treatment with Lutetium Lu 177 Vipivotide Tetraxetan PSMA is applied.

This medicine should only be administered by or under the direct supervision of a doctor trained in nuclear medicine.

Before using Locametz

When deciding to use a diagnostic test, any risks associated with the test must be weighed against the benefits it provides. This is a decision that you and your doctor will make. Other things can also influence the test results. For this test the following should be taken into account:

Allergies

Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also tell your doctor if you have other allergies, such as to foods, dyes, preservatives or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatrics

No relevant studies have been conducted on the association of age with the effects of Illuccix® and Locametz® in children and adolescents. Safety and effectiveness have not been established.

The use of gallium Ga-68-PSMA-11 injection in children is not indicated.

geriatrics

Related studies conducted to date have not shown any geriatric-specific problems that would limit the benefit of gallium Ga-68-PSMA-11 injection in the elderly.

Breastfeeding

There are insufficient studies in women to determine the risk to infants when using this drug while breast-feeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug interactions

Although certain medicines should not be used together at all, in other cases two different medicines can be used together, although interactions may occur. In these cases, your doctor may want to change the dose or other precautions may be necessary. Tell your doctor if you are taking other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be taken during or near food or consumption of certain foods because interactions may occur. Consuming alcohol or tobacco with certain medications can also lead to interactions. Discuss using your medicine with food, alcohol or tobacco with your doctor.

Proper use of Locametz

A doctor or other trained healthcare professional will give you this medicine. This medicine is given through a needle into one of your veins just before you have a PET scan.

Drink enough water before the PET scan to stay hydrated.

You must urinate as often as possible immediately and for at least 1 hour after the PET scan.

Precautions when using Locametz

It is very important that your doctor checks you closely while you are receiving this medicine. This will help your doctor determine whether the medicine is working properly and decide whether you should continue to receive it.

While you are receiving this medicine, you will be exposed to radiation and increase your risk of cancer. If you have any questions about this, talk to your doctor.

Side effects of Locametz

In addition to the necessary effects, a medicine may also have some undesirable effects. Although not all of these side effects may occur, medical attention may be required if they occur.

Some side effects may occur that usually do not require medical attention. These side effects may disappear during treatment as your body gets used to the medicine. Your doctor may also be able to give you ways to prevent or reduce some of these side effects. If any of the following side effects persist or are bothersome, or if you have any questions, contact your doctor:

Less common

• Ungewöhnliche Müdigkeit oder Schwäche

Rarely

• Blutungen, Blasenbildung, Brennen, Kälte, Verfärbung der Haut, Druckgefühl, Nesselsucht, Infektion, Entzündung, Juckreiz, Knoten, Taubheitsgefühl, Schmerzen, Hautausschlag, Rötung, Narbenbildung, Schmerzen, Stechen, Schwellung, Empfindlichkeit, Kribbeln, Geschwüre oder Wärme an der Injektionsstelle
• Verstopfung
• Durchfall
• Schwindel
• trockener Mund
• Brechreiz
• Erbrechen

Some patients may also experience other side effects not listed. If you notice other side effects, contact your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Commonly used brand names

In the USA

• Illuccix
• Locametz

Available dosage forms:

• Lösung

More information