Milnacipran

Milnacipran

Milnacipran

What is Milnacipran?

Milnacipran may also be used for purposes not listed in this medication guide.

Milnacipran side effects

If necessary, get emergency medical helpSigns of an allergic reaction: hives; difficult breathing; Swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: B. Mood or behavior changes, depression, anxiety, panic attacks, sleep problems, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless or hyperactive (mentally or physically). or have thoughts about suicide or self-harm.

Milnacipran can cause serious side effects. Call your doctor immediately if you have:

• little or no urination;

• blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;

• a seizure;

• a light-headed feeling, as if you were going to faint;

• Liver problems – stomach pain (top right), itching, dark urine, jaundice (yellowing of the skin or eyes);

• low sodium levels – headache, confusion, severe weakness, vomiting, problems with thinking or memory, feeling unsteady; or

• Manic episodes – racing thoughts, increased energy, unusual risk-taking behavior, extreme happiness, irritability or talkativeness.

Seek immediate medical attention if you have symptoms of serotonin syndrome, such as:Restlessness, hallucinations, fever, sweating, shaking, fast heartbeat, muscle stiffness, twitching, loss of coordination, nausea, vomiting or diarrhea.

Some side effects may be more likely in older adults.

Common side effects of milnacipran may include:

• nausea, vomiting, constipation;

• dry mouth;

• increased blood pressure;

• fast or pounding heartbeat;

• increased sweating, feeling hot (warmth, redness or tingling);

• headache, dizziness; or

• Sleep disorders.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to FDA at 1-800-FDA-1088.

Warnings

Some young people have suicidal thoughts when they first take milnacipran. Watch for mood changes or symptoms.

Do not use milnacipran if you have taken an MAO inhibitor in the past 14 days.such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline or tranylcypromine. After you stop taking milnacipran, you must wait at least 5 days before starting to take an MAOI.

Milnacipran is not approved for use by people under 18 years of age.

Do not stop using milnacipran without asking your doctor first.

Before you take this medicine

You should not use milnacipran if you are allergic to it.

Do not use milnacipran if you have taken an MAO inhibitor in the past 14 days. Dangerous drug interactions could occur. MAOIs include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, and tranylcypromine. After you stop taking milnacipran, you must wait at least 5 days before starting to take an MAOI.

Milnacipran should not be given to children under 18 years of age.

Tell your doctor if you have ever had:

• liver disease;

• kidney disease;

• heart disease, high blood pressure;

• seizures or epilepsy;

• bipolar disorder (manic depression);

• bleeding problems;

• low levels of sodium in your blood;

• sexual problems;

• if you drink alcohol; or

• if you are taking a blood thinner such as warfarin (Coumadin, Jantoven).

Make sure your doctor knows if you also take stimulants, opioid medications, herbal products, or medications for depression, mental illness, Parkinson's disease, migraines, serious infections, or to prevent nausea and vomiting. These medicines can interact with milnacipran and cause a serious condition called serotonin syndrome.

Some young people have suicidal thoughts when they first take milnacipran. Your doctor should check your progress at regular visits. Your family or other caregivers should also monitor for mood changes or symptoms.

Taking this drug during pregnancy may cause serious lung problems or other complications in the baby. Tell your doctor immediately if you become pregnant.Do not start or stop taking this medicine during pregnancy without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of milnacipran on the baby.

Breastfeeding may not be safe while using this medication. Ask your doctor about any risks.

How should I take milnacipran?

Follow all instructions on your prescription label and read any medication guides or instructions for use. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Tell your doctor if you feel an increased urge to take more milnacipran.

You can take the medicine with or without food, but food may help you tolerate the medicine better.

Your blood pressure and heart rate will need to be checked frequently.

Tell your doctor if you experience changes in sexual function, such as: B. a loss of interest in sex, problems with orgasm, or (in men) problems with erections or ejaculation. Some sexual problems can be treated.

Do not stop using milnacipran suddenly or you may experience unpleasant withdrawal symptoms. Ask your doctor how to safely stop using milnacipran.

Store at room temperature, protected from moisture and heat.

Milnacipran dosage information

Usual Adult Dose for Fibromyalgia:

Maintenance dose: 50 mg orally twice daily
Maximum dose: 100 mg orally twice daily (200 mg orally per day)

Comments:
-The dosage can be titrated according to the following scheme:
-Initial dose on day 1: 12.5 mg orally once
-Days 2 and 3: 12.5 mg orally twice daily
-Days 4 to 7: 25 mg orally twice daily
-After day 7: 50 mg orally twice daily

Uses: Treatment of fibromyalgia

What happens if I miss a dose?

Take the medicine as soon as possible, but skip the missed dose if it is almost time for the next dose. Do not take two doses at the same time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help hotline at 1-800-222-1222.

Symptoms of overdose may include extreme drowsiness, slow heartbeat, weak pulse, fainting, and slow breathing (breathing may stop).

What should I avoid while taking milnacipran?

Avoid driving and dangerous activities until you know how milnacipran affects you. Your reactions may be affected.

Avoid alcohol.

Consult your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Using an NSAID with milnacipran may cause easy bruising or bleeding.

What other drugs will affect milnacipran?

Using milnacipran with other medications that make you sleepy may worsen this effect. Consult your doctor before taking opioid medications, sleeping pills, muscle relaxants, or anti-anxiety or seizure medications.

Other medications can affect milnacipran, including prescription and over-the-counter medications, vitamins, and herbal products. Tell your doctor about all medications you are currently taking and any medications you are taking or stopping.

More information

Remember to keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the prescribed indication.