Rixubis

Rixubis

Rixubis

What is Rixubis?

Rixubis may also be used for purposes not listed in this medication guide.

Rixubis side effects

If necessary, get emergency medical helpSigns of an allergic reaction:hives, itching; Wheezing, chest tightness, difficulty breathing, fast heartbeat, blue lips, feeling like you might faint; Swelling of your face, lips, tongue, or throat.

Rixubis can cause serious side effects. Call your doctor immediately if you have:

• weight gain, swelling of the waist, hands or lower legs;

• loss of appetite;

• fever or chills;

• persistent bleeding after treatment;

• new or worse bleeding; or

• Signs of excessive blood clotting - sudden numbness or weakness (especially on one side of the body), slurred speech, problems with vision or balance, chest pain, coughing up blood or pain, swelling, warmth and redness in one or both legs.

Common side effects of Rixubis may include:

• nausea;

• Headache;

• Dizziness;

• altered sense of taste;

• mild rash; or

• Pain, redness, itching, stinging, or other irritation at the injection site of the drug.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to FDA at 1-800-FDA-1088.

Warnings

Follow all instructions on the label and packaging of your medicine. Tell each of your healthcare providers about all your medical conditions, allergies and any medications you take.

Before you take this medicine

You should not use Rixubis if:

• you have had an allergic reaction to clotting factor medications;

• you have signs of excessive blood clotting; or

• You are allergic to hamster proteins.

Tell your doctor if you have ever had:

• kidney disease;

• liver disease;

• coronary heart disease (hardening of the arteries); or

• a heart attack or stroke.

Tell your doctor if you are pregnant or breastfeeding.

Rixubis is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination. However, there is still a small possibility that it could transmit disease. Ask your doctor about possible risks.

How should I use Rixubis?

Follow all instructions on your prescription label and read any medication guides or instructions for use. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may receive your first dose in a hospital or clinic to quickly treat serious side effects.

Rixubis is given as an infusion into a vein. A doctor will give you the first dose and may teach you how to properly use the medication yourself.

Carefully read and follow all instructions for use that come with your medicine. Ask your doctor or pharmacist if you do not understand all the instructions.

Rixubis must be mixed with a liquid (diluent) before use. If you are administering injections yourself, make sure you know how to properly mix and store the medicine.

The mixture should appear clear, yellow or colorless. Do not prepare an injection until you are ready to give it. Do not use if the medicine looks cloudy, has changed color, or contains particles. Call your pharmacist for a new medicine.

Stir the medicine gently, but do not shake it while mixing or it may ruin it. Use the injection within 3 hours of mixing your dose.

Frequent blood tests may be necessary.

In an emergency, carry a medical ID to let others know that you have a blood clotting disorder.

Carefully follow the instructions on your medicine label for storing the powdered medicine and diluent. Some forms of clotting factor IX can be stored at room temperature, but others should be kept in the refrigerator. Do not freeze. Do not expose the medication to light.

Each vial (bottle) is for single use only. Throw it away after one use, even if it still contains medicine.

Throw away any leftover Rixubis once the expiration date stated on the label has passed.

Use the needle and syringe only once and then place them in a puncture-proof sharps container. Follow state or local laws regarding disposal of this container. Keep it out of the reach of children and pets.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help hotline at 1-800-222-1222.

What should I avoid when using Rixubis?

Follow your doctor's instructions regarding any food, drink, or activity restrictions.

What other drugs will affect Rixubis?

Other medications can affect Rixubis, including prescription and over-the-counter medications, vitamins, and herbal products. Tell your doctor about all medications you are currently taking and any medications you are taking or stopping.

More information

Remember to keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the prescribed indication.