Simulect

Simulect

Simulect

What is Simulect?

Simulect may also be used for purposes not listed in this medication guide.

Simulate side effects

If necessary, get emergency medical helpSigns of an allergic reaction: hives, rash, itching; the feeling of fainting; sneezing, wheezing, difficulty breathing; rapid heartbeat; Swelling of your face, lips, tongue, or throat.

An allergic reaction can occur up to 24 hours after a Simulect injection.

Simulect can cause serious side effects. Call your doctor immediately if you have:

• difficulty breathing;

• pain or burning when urinating;

• joint pain, redness, or stiffness;

• a surgical wound that does not heal;

• easy bruising, unusual bleeding, purple or red spots under the skin;

• swelling of hands or feet;

• high blood sugar – increased thirst, increased urination, dry mouth, fruity breath smell;

• high levels of potassium in the blood – nausea, weakness, tingling, chest pain, irregular heartbeat, loss of movement;

• low levels of potassium in the blood - leg cramps, constipation, irregular heartbeat, fluttering in the chest, increased thirst or need to urinate, numbness or tingling, muscle weakness or feeling weak;

• low red blood cells (anemia) – pale skin, tiredness, lightheadedness or shortness of breath, cold hands and feet; or

• Signs of infection – fever, chills, sore throat, body aches, unusual tiredness, vomiting, diarrhea.

Common side effects of Simulect may include:

• stomach pain or upset stomach, nausea, vomiting;

• diarrhea, constipation;

• Cold symptoms such as stuffy nose, sore throat;

• Headache;

• increased blood pressure;

• Tremble;

• sleep problems (insomnia);

• Acne; or

• Swelling of your hands, ankles or feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to FDA at 1-800-FDA-1088.

Warnings

You may get infections or bleed more easily. Call your doctor if you experience unusual bleeding or signs of infection (fever, cough, skin sores, painful urination).

Before you take this medicine

You should not use Simulect if you are allergic to it.

Tell your doctor if you have ever had:

• Cancer;

• Diabetes;

• high cholesterol; or

• an electrolyte imbalance (e.g. high or low levels of potassium in your blood);

May harm an unborn child.Use effective contraception while taking Simulect and for at least 4 months after your last dose. Tell your doctor if you become pregnant.

Don't breastfeed.

How is Simulect deployed?

Simulect is injected into a vein by a healthcare provider.

Simulect must be administered slowly over 30 minutes.

Simulect is usually given immediately before your transplant and again 4 days after.

You may get infections or bleed more easily. You need medical tests.

What happens if I miss a dose?

In a medical setting, you are unlikely to miss a dose.

What happens if I overdose?

In the medical field, an overdose would be treated quickly.

What should I avoid when receiving Simulect?

Avoid vaccination with a live vaccine, otherwise a serious infection could occur. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles). Ask your doctor how soon after treatment you can safely receive a live vaccine.

Avoid being near sick or infected people. Tell your doctor immediately if you notice any signs of infection.

What other drugs will affect Simulect?

Other medications may affect Simulect, including prescription and over-the-counter medications, vitamins, and herbal products. Tell your doctor about all other medicines you are taking.

More information

Remember to keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the prescribed indication.