Sumatriptan (oral)

Sumatriptan (oral)

Uses for sumatriptan

Many people find that their headaches disappear completely after taking sumatriptan. Other people find that their headaches are much less painful and that they can go about their normal activities even if the headache has not completely gone away. Sumatriptan often relieves other symptoms that occur with migraine headaches, such as nausea, vomiting, and sensitivity to light and sound.

Sumatriptan is not an ordinary painkiller. It does not relieve pain other than migraine headaches. This medicine is usually used in people whose headaches are not relieved by acetaminophen, aspirin, or other painkillers.

Sumatriptan has caused serious side effects in some people, especially those with heart or blood vessel disease. Be sure to discuss with your doctor the risks of using this medication as well as the possible benefits.

This medicine is only available with a doctor's prescription.

Before using sumatriptan

When deciding whether to use a medicine, the risks of taking the medicine must be weighed against the benefits it produces. This is a decision that you and your doctor will make. The following should be noted with this medicine:

Allergies

Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also tell your doctor if you have other allergies, such as to foods, dyes, preservatives or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatrics

No appropriate studies have been conducted on the relationship between age and the effects of sumatriptan in children and adolescents. Safety and effectiveness have not been established.

geriatrics

The use of sumatriptan is not recommended in elderly patients with kidney problems, heart or blood vessel disease, or high blood pressure, and should not be used in elderly patients with liver problems.

Breastfeeding

There are insufficient studies in women to determine the risk to infants when using this drug while breast-feeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug interactions

Although certain medicines should not be used together at all, in other cases two different medicines can be used together, although interactions may occur. In these cases, your doctor may want to change the dose or other precautions may be necessary. If you are taking this medicine, it is particularly important that your doctor knows whether you are taking any of the medicines listed below. The following interactions were selected for their potential significance and are not necessarily exhaustive.

The use of this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or to change some of the other medications you are taking.

• Almotriptan
• Bromocriptin
• Dihydroergotamin
• Eletriptan
• Ergoloidmesylate
• Ergonovin
• Ergotamin
• Frovatriptan
• Furazolidon
• Iproniazid
• Isocarboxazid
• Linezolid
• Methylenblau
• Methylergonovin
• Methysergid
• Moclobemid
• Naratriptan
• Nialamid
• Phenelzin
• Procarbazin
• Rasagilin
• Rizatriptan
• Safinamid
• Selegilin
• Tranylcypromin
• Zolmitriptan

Using this medicine with any of the following medicines is not usually recommended but may be necessary in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both medicines.

• Alfentanil
• Amineptin
• Amitriptylin
• Amitriptylinoxid
• Amoxapin
• Amphetamin
• Benzhydrocodon
• Benzphetamin
• Buprenorphin
• Bupropion
• Butorphanol
• Citalopram
• Clomipramin
• Kodein
• Desipramin
• Desvenlafaxin
• Dexfenfluramin
• Dextroamphetamin
• Dextromethorphan
• Dibenzepin
• Dihydrocodein
• Dolasetron
• Doxepin
• Duloxetin
• Escitalopram
• Fenfluramin
• Fentanyl
• Fluoxetin
• Fluvoxamin
• Gepiron
• Granisetron
• Hydrocodon
• Hydromorphon
• Hydroxyamphetamin
• Imipramin
• Lasmiditan
• Levomilnacipran
• Levorphanol
• Lisdexamfetamin
• Lithium
• Lofepramin
• Lorcaserin
• Melitracen
• Meperidin
• Metaxalone
• Methamphetamin
• Milnacipran
• Mirtazapin
• Morphium
• Morphinsulfat-Liposom
• Nalbuphin
• Nefazodon
• Nortriptylin
• Ondansetron
• Opipramol
• Oxycodon
• Oxymorphon
• Palonosetron
• Paroxetin
• Pentazocin
• Protriptylin
• Reboxetin
• Remifentanil
• Sertralin
• Sibutramin
• Johanniskraut
• Sufentanil
• Tapentadol
• Tianeptin
• Tramadol
• Trazodon
• Trimipramin
• Venlafaxin
• Vilazodon
• Vortioxetin
• Ziprasidon

Interactions with food/tobacco/alcohol

Certain medicines should not be taken during or near food or consumption of certain foods because interactions may occur. Consuming alcohol or tobacco with certain medications can also lead to interactions. Discuss using your medicine with food, alcohol or tobacco with your doctor.

Other medical problems

The presence of other medical problems may affect the use of this medicine. Be sure to tell your doctor if you have any other medical problems, especially:

• Angina (Brustschmerzen) oder
• Arrhythmie (Herzrhythmusstörung) oder
• Basiläre Migräne (Migräne mit Seh- und Hörproblemen) oder
• Zerebrovaskuläre Erkrankungen (z. B. Schlaganfall, transitorische ischämische Attacke) oder Vorgeschichte von oder
• Herzinfarkt, Geschichte von oder
• Herz- oder Blutgefäßprobleme oder
• Hemiplegische Migräne (Migräne mit etwas Lähmung) oder
• Hypertonie (Bluthochdruck), unkontrollierte oder
• Ischämische Darmerkrankung (Darm ist schlecht durchblutet) oder
• Lebererkrankung, schwere oder
• Periphere Gefäßerkrankung (verstopfte Arterien) oder
• Schlaganfall, Geschichte von oder
• Vorübergehender ischämischer Anfall (TIA), Vorgeschichte von oder
• Wolff-Parkinson-White-Syndrom (Herzrhythmusstörung) – Sollte bei Patienten mit diesen Erkrankungen nicht angewendet werden.

• Anfälle oder Epilepsie, Vorgeschichte von oder
• Magen- oder Darmblutungen – Mit Vorsicht anwenden. Kann diese Bedingungen verschlimmern.

• Koronare Herzkrankheit, Vorgeschichte von oder
• Diabetes bzw
• Hypercholesterinämie (hoher Cholesterinspiegel im Blut) oder
• Hypertonie (Bluthochdruck), kontrollierte oder
• Lebererkrankung, leicht bis mittelschwer oder
• Fettleibigkeit bzw
• Raynaud-Syndrom – Mit Vorsicht anwenden. Möglicherweise besteht ein erhöhtes Risiko für schwerwiegendere Nebenwirkungen.

Correct use of sumatriptan

Do not use this medicine for headaches that are different from your usual migraine attacks. Talk to your doctor about what you can do if you have regular headaches.

To relieve your migraine as quickly as possible, use this medicine as soon as the headache begins. Even if you experience warning signs of an impending migraine (aura), you should wait until the headache starts before using sumatriptan.

Ask your doctor in advance about other medicines you may be taking if sumatriptan does not work. After using the other medicine, contact your doctor as soon as possible. Headaches that are not relieved by sumatriptan are sometimes caused by medical conditions that require other treatment.

If you feel significantly better after a dose of sumatriptan, but your headache comes back or gets worse after a while, wait at least 2 hours before taking another dose. However, only use this medicine as directed by your doctor. Do not use more or more often than directed. Taking too much sumatriptan may increase your risk of side effects. Do not take more than 200 mg in 24 hours.

Swallow the tablet whole with water or other liquid. Do not crush, break or chew it.

You can take the tablet with or without food.

This medicine comes with a package leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

dosage

The dose of this medicine is different for different patients. Follow your doctor's instructions or the label directions. The following information includes average doses of this medicine only. If your dose is different, do not change it unless your doctor tells you to.

The amount of medicine you take depends on the strength of the medicine. In addition, the number of doses you take each day, the time between doses, and how long you take the medicine depend on the medical problem for which you are using the medicine.

• Für orale Darreichungsform (Tabletten):
  • Bei Migränekopfschmerzen:
    • Erwachsene – 25, 50 oder 100 Milligramm (mg) als Einzeldosis. Wenn Sie eine gewisse Linderung verspüren oder die Migräne nach der Linderung erneut auftritt, kann 2 Stunden nach der letzten Dosis eine weitere Dosis eingenommen werden. Nehmen Sie innerhalb von 24 Stunden nicht mehr als 200 mg ein.
    • Kinder – Anwendung und Dosis müssen von Ihrem Arzt festgelegt werden.

storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Protect from freezing.

Keep away from children.

Do not keep medications that are outdated or no longer needed.

Ask your doctor how to throw away medicines you don't use.

Precautions when using sumatriptan

It is very important that your doctor check your progress at regular visits. This will help your doctor determine whether the medicine is working properly and decide whether you should continue using it.

Ask your doctor if you have used this medicine and it does not work. Also ask your doctor if your migraine headaches have gotten worse or if they have occurred more frequently since you started using this medication.

You should not use this medicine if you have taken an MAO inhibitor (MAOI) such as phenelzine (Nardil®) or tranylcypromine (Parnate®) within the last 2 weeks. Do not use this medicine if you have taken other triptan migraine medicines or ergot-type medicines within the last 24 hours. Some examples of triptan medicines are almotriptan (Axert®), eletriptan (Relpax®), naratriptan (Amerge®), or zolmitriptan (Zomig®). Some examples of ergot-type drugs are dihydroergotamine (DHE 45®, Migranal®), ergotamine (Bellergal®, Cafergot®, Ergomar®, Wigraine®) or methysergide (Sansert®).

This medicine may cause problems if you have heart disease. If your doctor thinks you may have a problem with this medication, he or she may want you to take your first dose in the doctor's office or clinic.

This medicine may increase your risk of irregular heartbeat, heart attack, angina, or stroke. This is more likely if you or a family member already has heart disease, if you have diabetes, high blood pressure or high cholesterol, or if you smoke. Call your doctor immediately if you have symptoms of a heart problem, such as: B. Chest pain or discomfort, irregular heartbeat, nausea or vomiting, pain or discomfort in the shoulders, arms, jaw, back or neck, shortness of breath, or sweating. Call your doctor immediately if you notice symptoms of a stroke, such as: B. Confusion, difficulty speaking, double vision, headache, inability to move arms, legs, or facial muscles, inability to speak, or slow speech.

Consult your doctor immediately if you experience chest, jaw, or neck discomfort after using this medication. Also tell your doctor if you experience sudden or severe abdominal or stomach pain or bloody diarrhea after using this medication.

Contact your doctor immediately if blurred vision, difficulty reading, or other vision problems occur during or after treatment. You may need to have your eyes examined by an ophthalmologist (ophthalmologist).

Using sumatriptan alone or in combination with other migraine medications for 10 or more days per month may cause headaches to worsen. You can keep a headache diary to record the frequency of your headaches and drug use.

Make sure your doctor knows about any other medicines you are taking. Taking sumatriptan with some medicines can cause a serious condition called serotonin syndrome. These include in particular medicines for the treatment of depression such as citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine, Celexa®, Cymbalta®, Effexor®, Lexapro®, Luvox®, Paxil®, Prozac®, Sarafem®, Symbyax® or Zoloft®. Contact your doctor immediately if you experience agitation, confusion, diarrhea, unusual excitement when speaking, fever, overactive reflexes, poor coordination, restlessness, trembling, sweating, shaking or shaking that you cannot control, or twitching. These could be symptoms of serotonin syndrome.

This medicine can cause a serious allergic reaction called anaphylaxis. Anaphylaxis requires immediate medical attention. The most serious signs of this reaction are very rapid or irregular breathing, shortness of breath, wheezing, or fainting. Other signs may include changes in facial skin, very fast but irregular heartbeat or pulse, hive-like swellings on the skin, and swelling or puffiness of the eyelids or around the eyes. If these effects occur, get emergency help immediately.

Consuming alcoholic beverages may make headaches worse or cause new headaches to occur. People who suffer from severe headaches should avoid alcoholic beverages, especially during the headache.

Some people feel dizzy or sleepy during or after a migraine, or after using sumatriptan to relieve a migraine. If you feel dizzy or sleepy, do not drive, operate machinery, or do other activities that could be dangerous if you are dizzy or inattentive.

Side effects of sumatriptan

In addition to the necessary effects, a medicine may also have some undesirable effects. Although not all of these side effects may occur, medical attention may be required if they occur.

Consult your doctor immediately if any of the following side effects occur:

Less common

• Bauch- oder Magenschmerzen
• Angst
• verschwommene Sicht
• Veränderungen in den Mustern und Rhythmen der Sprache
• Brustschmerzen oder Engegefühl
• Schüttelfrost
• Verwirrung
• Schwindel
• schneller, langsamer, unregelmäßiger, hämmernder oder rasender Herzschlag oder Puls
• Kopfschmerzen
• Muskelkrämpfe und Steifheit
• Nacken-, Hals- oder Kieferschmerzen
• Albträume
• Zittern
• Schwitzen
• Schwellung der Finger, Hände, Füße oder Unterschenkel
• Engegefühl in der Brust
• Atembeschwerden

Rarely

• Blindheit
• Brustschmerzen oder Unwohlsein
• Engegefühl oder Schweregefühl in der Brust
• Rötung oder Rötung der Haut, insbesondere im Gesicht und am Hals
• vermehrtes Blinzeln oder Krämpfe des Augenlids
• Juckreiz, Schmerzen, Rötung oder Schwellung
• Benommenheit, Schwindel oder Ohnmacht
• Nervenschmerzen
• starkes Taubheitsgefühl, insbesondere auf einer Seite des Gesichts oder des Körpers
• starke oder anhaltende Magenschmerzen
• Schwierigkeiten beim Sprechen oder Schlucken
• Zucken
• ungewöhnliche Blutungen oder Blutergüsse
• Erbrechen von Blut oder Material, das wie Kaffeesatz aussieht
• Schwäche der Arme und Beine

Incident not known

• Agitation
• Rücken-, Bein- oder Bauchschmerzen
• Zahnfleischbluten
• Veränderungen im Sehvermögen
• Muskelzuckungen
• Punktgenaue rote Flecken auf der Haut
• schlechte Koordination
• Schwellungen oder Schwellungen der Augenlider oder um die Augen, das Gesicht, die Lippen oder die Zunge
• Unruhe
• Hautausschlag, Nesselsucht oder Juckreiz
• unerklärliche Blutungen oder Blutergüsse
• ungewöhnlich warme Haut
• Schwäche im Arm oder Bein auf einer Körperseite, plötzlich und schwerwiegend

Some side effects may occur that usually do not require medical attention. These side effects may disappear during treatment as your body gets used to the medicine. Your doctor may also be able to give you ways to prevent or reduce some of these side effects. If any of the following side effects persist or are bothersome, or if you have any questions, contact your doctor:

Less common

• Brennen, Krabbeln, Jucken, Taubheitsgefühl, Kribbeln, „Ameisenlaufen“ oder Kribbeln
• Veränderung des Farbsehens
• Veränderung des Gehörs
• Konzentrationsschwierigkeiten
• Schläfrigkeit
• Sodbrennen
• erhöhte Empfindlichkeit der Augen gegenüber Sonnenlicht
• Gelenkschmerzen
• Muskelschmerzen oder Krämpfe
• Muskelsteifheit oder -verspannungen
• geschwollene Gelenke
• Schlafstörungen

Rarely

• Aggressivität
• Aufstoßen
• Geschmacksveränderung
• Ich spüre Lichthöfe um Lichter herum
• erhöhte Schmerzempfindlichkeit
• Appetitverlust
• Taubheitsgefühl, Schmerzen, Kribbeln oder Schwäche
• Magenbeschwerden oder Magenverstimmung
• Kribbeln in den Händen und Füßen
• Tunnelblick
• Schwäche

Some patients may also experience other side effects not listed. If you notice other side effects, contact your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Commonly used brand names

In the USA

• Imitrex

Available dosage forms:

• Tablette

Therapeutic Class: Antimigraine

Pharmacological class: Serotonin receptor agonist, 5-HT1

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