Trumenba (intramuscular, subcutaneous)

Trumenba (intramuscular, subcutaneous)

Trumenba (intramuscular, subcutaneous)

Uses for Trumenba

The meningococcal vaccine is an active immunizing agent used to prevent infections caused by certain groups of meningococcal bacteria (Neisseria meningitides). The vaccine causes your body to produce its own protection (antibodies) against the disease.

Bexsero® and Trumenba® only work against group B meningococcal bacteria.

Meningococcal infection can cause life-threatening diseases such as meningococcal meningitis, which affects the brain, and meningococcal infection, which affects the blood. Some people with meningococcal meningitis and/or meningococcemia may also die. These diseases are more common in young children and in people with certain diseases or conditions that make them more susceptible to meningococcal infection or increase the likelihood that they will develop serious problems due to meningococcal infection.

Vaccination against meningococcal disease is recommended for people who are at risk of developing the disease because:

• Sie haben bestimmte Krankheiten oder Zustände, die sie anfälliger für eine Meningokokken-Infektion machen oder die Wahrscheinlichkeit erhöhen, dass sie aufgrund einer Meningokokken-Infektion ernsthafte Probleme entwickeln.
• Sie leben, arbeiten oder besuchen ein Gebiet, in dem ein hohes Risiko einer Meningokokken-Erkrankung besteht.

Menomune® is recommended for use in patients 2 years of age and older.

Bexsero® and Trumenba® are recommended for use in patients aged 10 to 25 years. .

This vaccine should only be given by or under the supervision of your doctor.

Before using Trumenba

When deciding whether to use a vaccine, the risks of vaccination must be weighed against the benefits it brings. This is a decision that you and your doctor will make. The following should be taken into account with this vaccine:

Allergies

Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also tell your doctor if you have other allergies, such as to foods, dyes, preservatives or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatrics

No relevant studies have been conducted on the association of age with the effects of Menomune® in children under 2 years of age. However, in some cases, children as young as 3 months old can also be vaccinated.

No relevant studies have been conducted on the association of age with the effects of Bexsero® and Trumenba® in children under 10 years of age. Safety and effectiveness have not been established.

geriatrics

No appropriate studies have been conducted on the association between age and the effects of meningococcal vaccination in adults over 65 years of age. Safety and effectiveness have not been established.

Breastfeeding

Meningococcal polysaccharide vaccine, diphtheria conjugateMeningococcal polysaccharide vaccine

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Meningococcal vaccine, group BMeningococcal oligosaccharide vaccine, diphtheria conjugateMeningococcal vaccine, tetanus toxoid conjugate quadrivalent

There are insufficient studies in women to determine the risk to infants when using this drug while breast-feeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug interactions

Although certain medicines should not be used together at all, in other cases two different medicines can be used together, although interactions may occur. In these cases, your doctor may want to change the dose or other precautions may be necessary. If you are receiving this vaccine, it is especially important that your doctor knows if you are taking any of the medicines listed below. The following interactions were selected for their potential significance and are not necessarily exhaustive.

Vaccination with any of the following medicines is not usually recommended but may be necessary in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both medicines.

• Elivaldogene Autotemcel
• Masernvirus-Impfstoff, lebend
• Teplizumab-mzwv
• Ublituximab-xiiy

Interactions with food/tobacco/alcohol

Certain medicines should not be taken during or near food or consumption of certain foods because interactions may occur. Consuming alcohol or tobacco with certain medications can also lead to interactions. Discuss using your medicine with food, alcohol or tobacco with your doctor.

Other medical problems

The presence of other medical problems may affect the use of this vaccine. Be sure to tell your doctor if you have any other medical problems, especially:

• Probleme mit dem Immunsystem – Mit Vorsicht anwenden. Kann die Wirkung dieses Impfstoffs verringern.

• Schwere Erkrankung mit Fieber – Die Symptome der Erkrankung können mit den möglichen Nebenwirkungen des Impfstoffs verwechselt werden.

Proper use of Trumenba

A nurse or other trained health professional will give this vaccine to you or your child. It is given as an injection under the skin or into one of your muscles.

Trumenba®: An injection is given into a muscle. It is very important that you or your child receive all vaccinations.

• Zwei-Dosen-Schema: Im Abstand von mindestens 6 Monaten (0 und 6 Monate) verabreicht. Wenn die zweite Dosis früher als 6 Monate nach der ersten Dosis verabreicht wird, erhalten Sie eine dritte Dosis mindestens 4 Monate nach der zweiten Dosis.
• Drei-Dosen-Schema: Nachdem Sie die erste Dosis erhalten haben (0 Monate), erhalten Sie nach 1 bis 2 Monaten eine zweite Dosis. Die dritte Dosis wird 6 Monate nach der ersten Dosis verabreicht.

Bexsero®: An injection is given into a muscle. Two doses, each at least a month apart. It is very important that you or your child receive both vaccinations.

Menomune®: One dose is injected under the skin. Typically, a person only needs to receive the vaccine once. However, additional injections may be needed in young children who remain at high risk of meningococcal disease.

Missed dose

Call your doctor or pharmacist for instructions.

Precautions when using Trumenba

Be sure to tell your doctor about any side effects that occur after vaccination.

This vaccine can cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Tell your doctor immediately if you experience rash, itching, rapid heartbeat, difficulty breathing, difficulty swallowing, or swelling of your hands, face, or mouth after vaccination.

You may experience fainting while receiving this vaccine. Your doctor may want you to be observed after the injection to prevent and treat fainting spells.

The tip caps of Bexsero® prefilled syringes contain dry natural rubber (a derivative of latex), which may cause an allergic reaction in people sensitive to latex.

It is important that your doctor knows about any other vaccinations you or your child have recently received, including a flu shot.

This vaccine may not protect everyone who receives it. It is not suitable for treating the symptoms of meningococcal infection if you already have the disease.

Side effects of Trumenba

In addition to the necessary effects, a medicine may also have some undesirable effects. Although not all of these side effects may occur, medical attention may be required if they occur.

Contact your doctor or nurse immediately if any of the following side effects occur:

More common

• Schüttelfrost

Less common

• Fieber über 100 Grad F
• allgemeines Unwohlsein oder Krankheitsgefühl

Incident not known

• Husten
• Schwierigkeiten beim Atmen oder Schlucken
• Schwindel
• Ohnmacht
• schneller Herzschlag
• Nesselsucht, Juckreiz oder Hautausschlag
• Schwellungen oder Schwellungen der Augenlider oder um die Augen, das Gesicht, die Lippen oder die Zunge
• Rötung der Haut, insbesondere um die Ohren
• ungewöhnliche Müdigkeit oder Schwäche (plötzlich und schwerwiegend)

Some side effects may occur that usually do not require medical attention. These side effects may disappear during treatment as your body gets used to the medicine. Your doctor may also be able to give you ways to prevent or reduce some of these side effects. If any of the following side effects persist or are bothersome, or if you have any questions, contact your doctor:

More common

• Schwierigkeiten beim Bewegen
• Kopfschmerzen
• Gelenk- oder Muskelschmerzen
• Brechreiz
• Rötung, Empfindlichkeit, Schmerzen oder Schmerzen an der Injektionsstelle

Less common

• Harter Knoten an der Injektionsstelle

Incident not known

• Blasen an oder um die Injektionsstelle

Some patients may also experience other side effects not listed. If you notice other side effects, contact your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Commonly used brand names

In the USA

• Bexsero
• Menactra
• Menomune-A/C/Y/W-135
• MännerQuadfi
• Menveo
• Trumenba

Available dosage forms:

• Suspension
• Bausatz
• Lösung

Therapeutic Class: Vaccine

More information