Vabomers

Vabomers

What is Vabomere?

Vabomere is a combination medicine used to treat serious urinary tract infections in adults.

Vabomere may also be used for purposes not listed in this medication guide.

Side effects of Vabomere

If necessary, get emergency medical helpSigns of an allergic reaction(hives, difficulty breathing, swelling of the face or throat)or a severe skin reaction(Fever, sore throat, burning in the eyes, skin pain, red or purple rash that spreads and causes blistering and peeling).

Vabomere can cause serious side effects. Call your doctor immediately if you have:

• severe stomach pain, watery or bloody diarrhea;

• a seizure (convulsions);

• sores or white spots in your mouth or throat (yeast infection or “thrush”);

• severe tingling or numbness; or

• unusual bleeding or bruising.

Common side effects of Vabomere may include:

• Headache;

• Diarrhea; or

• Swelling or irritation at the injection site of the drug.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to FDA at 1-800-FDA-1088.

Warnings

Before receiving Vabomere, tell your doctor if you have a history of allergies to antibiotics.

Before you take this medicine

You may not be able to use this medicine if you have ever had an allergic reaction to antibiotics, including:

• meropenem or vaborbactam;

• Amoxicillin, Ampicillin, Augmentin, Timentin, Unasyn, Zosyn;

• dicloxacillin, nafcillin, oxacillin, ticarcillin; or

• any penicillin antibiotic.

To make sure Vabomere is safe for you, tell your doctor if you have ever had:

• an allergy to a cephalosporin antibiotic (cephalexin, cefdinir, Keflex, Omnicef ​​​​and others);

• a head injury or brain tumor;

• epilepsy or other seizure disorders; or

• Kidney disease (or if you are on dialysis).

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

Meropenem and vaborbactam can pass into breast milk, but there are no known effects on the breast-fed child. Tell your doctor if you are breast-feeding.

How is Vabomere administered?

Follow all instructions on your prescription label. Do not use Vabomere in larger or smaller amounts or for longer than recommended.

Vabomere is injected into a vein through an IV. You may be shown how to use an infusion at home. Do not give yourself this medicine if you do not know how to give the injection or how to properly dispose of needles, intravenous tubes, and other items used.

Vabomere is usually given every 8 to 12 hours for up to 14 days. This medicine must be given slowly and the infusion may take about 3 hours.

Vabomere is a powder medicine that must be mixed with a liquid (diluent) and then further diluted before use. If you are using the injections at home, make sure you know how to properly mix and store the medicine.

The diluted mixture must be used within 4 hours if you keep it at room temperature. If you store the infusion bag in the refrigerator, use it within 22 hours.Do not freeze.

Each disposable vial (bottle) of meropenem and vaborbactam powder is for single use only. Throw it away after one use, even if it still contains medicine.

Do not mix other injectable medications in the same IV bag or tubing that you used to give your Vabomere injection.

After the infusion, discard any unused medicine that remains in the infusion bag. Do not save it for later use.

Use this medicine for the full time prescribed. Your symptoms may improve before the infection has completely cleared up. Skipping doses may also increase the risk of another antibiotic-resistant infection. Vabomere does not treat viral infections such as colds or flu.

Your kidney function may need to be checked while you are using this medicine.

Store unmixed powder at room temperature, away from moisture and heat.

Use a disposable needle and syringe only once. Follow all state or local laws about throwing away used needles and syringes. Use a puncture-resistant sharps disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next scheduled dose. Do not take extra medicine to make up for a missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help hotline at 1-800-222-1222.

What should I avoid when using Vabomere?

Vabomere may cause confusion, headaches, or other side effects that may affect your thinking or reactions. Be careful when driving or doing anything that requires your attention.

Antibiotic medications can cause diarrhea, which may be a sign of a new infection. If you have watery or bloody diarrhea, call your doctor. Do not use antidiarrheal medication unless your doctor recommends it.

What other drugs affect vabomers?

Tell your doctor about all medications you are currently taking and any medications you are taking or stopping, especially:

• divalproex sodium;

• probenecid; or

• Valproic acid.

This list is not complete. Other medications may interact with meropenem and vaborbactam, including prescription and over-the-counter medications, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

• Welche Medikamente sind in Vabomere enthalten?

More information

Remember to keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the prescribed indication.