Vi-Atro (oral)

Vi-Atro (oral)

Vi-Atro (oral)

Possible uses for Vi-Atro

Diphenoxylate is chemically related to some narcotics and can be habit-forming if taken in larger doses than prescribed. If higher than normal doses of the combination are taken, the atropine produces unpleasant effects.

This medicine is only available with a doctor's prescription.

Before using Vi-Atro

When deciding whether to use a medicine, the risks of taking the medicine must be weighed against the benefits it produces. This is a decision that you and your doctor will make. The following should be noted with this medicine:

Allergies

Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also tell your doctor if you have other allergies, such as to foods, dyes, preservatives or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatrics

Studies conducted to date have not shown any pediatric-specific problems that would limit the benefit of the combination of diphenoxylate and atropine in children aged 13 years and older. Safety and effectiveness have not been established in children under 13 years of age. This medicine should not be used in children under 6 years of age because of the risk of respiratory depression (severe breathing problems) or coma (unconsciousness).

geriatrics

There is no information on the relationship between age and the effects of the combination of diphenoxylate and atropine in geriatric patients.

Breastfeeding

There are insufficient studies in women to determine the risk to infants when using this drug while breast-feeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug interactions

Although certain medicines should not be used together at all, in other cases two different medicines can be used together, although interactions may occur. In these cases, your doctor may want to change the dose or other precautions may be necessary. If you are taking this medicine, it is particularly important that your doctor knows whether you are taking any of the medicines listed below. The following interactions were selected for their potential significance and are not necessarily exhaustive.

The use of this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or to change some of the other medications you are taking.

• Ambenonium
• Nalmefen
• Naltrexon
• Kaliumcitrat
• Safinamid
• Samidorphan

Using this medicine with any of the following medicines is not usually recommended but may be necessary in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both medicines.

• Alfentanil
• Alprazolam
• Amantadin
• Amifampridin
• Amphetamin
• Benzhydrocodon
• Benzphetamin
• Bromazepam
• Bromoprid
• Buprenorphin
• Bupropion
• Butorphanol
• Calciumoxybat
• Cannabidiol
• Cannabis
• Carbinoxamin
• Cetirizin
• Citalopram
• Clobazam
• Clonazepam
• Clopidogrel
• Clozapin
• Kodein
• Daridorexant
• Desmopressin
• Desvenlafaxin
• Dexmedetomidin
• Dextroamphetamin
• Dextromethorphan
• Diazepam
• Dihydrocodein
• Donepezil
• Doxylamin
• Duloxetin
• Escitalopram
• Esketamin
• Fenfluramin
• Fentanyl
• Flibanserin
• Fluoxetin
• Fluvoxamin
• Furazolidon
• Gabapentin
• Gabapentin Enacarbil
• Gepiron
• Glucagon
• Glycopyrrolat
• Glycopyrroniumtosylat
• Granisetron
• Hydrocodon
• Hydromorphon
• Hydroxyamphetamin
• Iproniazid
• Isocarboxazid
• Ketamin
• Lacosamid
• Lasmiditan
• Lemborexant
• Levocetirizin
• Levomilnacipran
• Levorphanol
• Linezolid
• Lisdexamfetamin
• Lithium
• Lofexidin
• Lorazepam
• Loxapin
• Macimorelin
• Magnesiumoxybat
• Meclizin
• Meperidin
• Metaxalone
• Methacholin
• Methadon
• Methamphetamin
• Methylenblau
• Metoclopramid
• Midazolam
• Milnacipran
• Mirtazapin
• Moclobemid
• Morphium
• Morphinsulfat-Liposom
• Nalbuphin
• Olanzapin
• Ondansetron
• Oxycodon
• Oxymorphon
• Ozanimod
• Paroxetin
• Pentazocin
• Periciazin
• Phenelzin
• Phenobarbital
• Kaliumoxybat
• Pregabalin
• Primidon
• Procarbazin
• Quetiapin
• Rasagilin
• Remifentanil
• Remimazolam
• Revefenacin
• Ropeginterferon Alfa-2b-njft
• Scopolamin
• Secretin Human
• Selegilin
• Sertralin
• Natriumoxybat
• Sufentanil
• Tapentadol
• Tiotropium
• Topiramat
• Tramadol
• Tranylcypromin
• Trazodon
• Vilazodon
• Vortioxetin
• Zolpidem
• Zuranolon

Using this medicine with any of the following medicines may result in an increased risk of certain side effects, but using both medicines may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both medicines.

• Arbutamin

Interactions with food/tobacco/alcohol

Certain medicines should not be taken during or near food or consumption of certain foods because interactions may occur. Consuming alcohol or tobacco with certain medications can also lead to interactions. Discuss using your medicine with food, alcohol or tobacco with your doctor.

Other medical problems

The presence of other medical problems may affect the use of this medicine. Be sure to tell your doctor if you have any other medical problems, especially:

• Durch Antibiotika oder eine Infektion verursachter Durchfall, einschließlich Sepsis oder
• Obstruktive Gelbsucht – Sollte bei Patienten mit diesen Erkrankungen nicht angewendet werden.

• Down-Syndrom – Kann dazu führen, dass sich die Nebenwirkungen verschlimmern.

• Vergrößerte Prostata bzw
• Gallenblasenerkrankung bzw
• Glaukom oder
• Herzkrankheit bzw
• Hypertonie (Bluthochdruck) bzw
• Nierenerkrankung bzw
• Lebererkrankung bzw
• Myasthenia gravis (schwere Muskelschwäche) oder
• Probleme beim Wasserlassen bzw
• Magen- oder Darmprobleme (z. B. Verstopfung, Hiatushernie, Colitis ulcerosa) oder
• Schilddrüsenprobleme – Mit Vorsicht anwenden. Kann diese Bedingungen verschlimmern.

Proper use of Vi-Atro

Only take this medicine as directed by your doctor. Do not take more of it, do not take it more often, or take it for longer than your doctor prescribed.

Measure the oral fluid using a marked measuring spoon, oral syringe, or medicine cup.

In addition to taking medication for diarrhea, it is very important that you replace the fluid lost from the body and eat properly. For the first 24 hours, you should eat gelatin and drink plenty of caffeine-free, clear liquids such as ginger ale, decaffeinated cola, decaffeinated tea, and broth. During the next 24 hours, you may eat bland foods such as cooked cereal, bread, crackers, and applesauce. Fruits, vegetables, fried or spicy foods, bran, sweets, caffeine and alcoholic drinks can worsen the condition.

dosage

The dose of this medicine is different for different patients. Follow your doctor's instructions or the label directions. The following information includes average doses of this medicine only. If your dose is different, do not change it unless your doctor tells you to.

The amount of medicine you take depends on the strength of the medicine. In addition, the number of doses you take each day, the time between doses, and how long you take the medicine depend on the medical problem for which you are using the medicine.

• Bei starkem Durchfall:
  • Für die orale Darreichungsform (orale Flüssigkeit):
    • Erwachsene – Zu Beginn beträgt die Dosis 5 Milligramm (mg) (2 Teelöffel) drei- bis viermal täglich. Anschließend kann Ihr Arzt Ihre Dosis je nach Bedarf einmal täglich auf 5 mg (2 Teelöffel) reduzieren.
    • Kinder unter 12 Jahren – Die Verwendung wird nicht empfohlen.
  • Für orale Darreichungsform (Tabletten):
    • Erwachsene und Kinder ab 13 Jahren – Die Anfangsdosis beträgt 5 Milligramm (mg) (2 Tabletten) viermal täglich. Anschließend kann Ihr Arzt Ihre Dosis je nach Bedarf einmal täglich auf 5 mg (2 Tabletten) reduzieren.
    • Kinder im Alter von 6 bis unter 13 Jahren – Anwendung und Dosierung müssen von Ihrem Arzt festgelegt werden.
    • Kinder unter 6 Jahren – Die Verwendung wird nicht empfohlen.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.

storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Protect from freezing.

Keep away from children.

Do not keep medications that are outdated or no longer needed.

Ask your doctor how to throw away medicines you don't use.

Precautions when using Vi-Atro

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for any unwanted side effects.

Diarrhea usually stops 2 days after treatment with this medicine. If your symptoms do not improve or worsen within 10 days of treatment, contact your doctor.

This medicine may cause serious stomach or intestinal problems (e.g. toxic megacolon). This is more likely if you also have ulcerative colitis. Consult your doctor immediately if you have bloating, constipation, loss of appetite, nausea, vomiting, or stomach pain.

Consult your doctor if you experience dizziness, rapid, shallow breathing, fast, weak heartbeat, headache, muscle cramps, pale, clammy skin, thirst, extremely high fever or body temperature, decreased amount of urine, decreased frequency of urination, difficulty urinating, painful urination, dry skin, and dry mouth. These may be signs of a condition called atropinism.

Consult your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). Consumption of alcohol or other drugs that affect the CNS in combination with diphenoxylate and atropine may worsen the side effects of this drug, such as dizziness, difficulty concentrating, drowsiness, unusual dreams, and difficulty sleeping. Some examples of medicines that affect the CNS are antihistamines or allergy or cold medicines, sedatives, sedatives or sleeping pills, depression medicines, anti-anxiety medicines, prescription painkillers or narcotics, attention deficit hyperactivity disorder medicines, and medicines for Seizures or barbiturates, muscle relaxants or anesthetics, including some dental anesthetics.

If you think you or someone else may have taken an overdose of this medicine, get emergency help immediately. Taking an overdose of this drug may cause loss of consciousness and possibly death. Signs or symptoms of overdose include severe sleepiness, shortness of breath or difficulty breathing, rapid heartbeat, and unusual warmth, dryness, and redness of the skin.

This medicine may cause dizziness or sleepiness. Do not drive or do other dangerous activities until you know how this medicine affects you.

Do not take any other medicines unless you have discussed this with your doctor. This includes both prescription and nonprescription (over-the-counter [OTC]) medications and herbal or vitamin supplements.

Side effects of Vi-Atro

In addition to the necessary effects, a medicine may also have some undesirable effects. Although not all of these side effects may occur, medical attention may be required if they occur.

Consult your doctor immediately if any of the following side effects occur:

Incident not known

• Blähungen
• Verwirrung
• Verstopfung
• Husten
• Verringerung der Häufigkeit des Wasserlassens
• Abnahme des Urinvolumens
• Durchfall
• Schwierigkeiten beim Wasserlassen (Tröpfeln)
• Schluckbeschwerden
• Entmutigung
• Schwindel
• Schläfrigkeit
• trockene Haut und Mund
• extrem hohes Fieber oder hohe Körpertemperatur
• falsches oder ungewöhnliches Wohlbefinden
• schnelles, flaches Atmen
• schneller, schwacher Herzschlag
• Gefühl von Wärme
• sich traurig oder leer fühlen
• Kopfschmerzen
• Nesselsucht, Juckreiz, Hautausschlag
• Reizbarkeit
• Appetitverlust
• Verlust von Interesse oder Vergnügen
• Muskelkrämpfe
• Brechreiz
• Taubheitsgefühl in Armen und Beinen
• schmerzhaftes Urinieren
• blasse, feuchte Haut
• Schwellungen oder Schwellungen der Augenlider oder um die Augen, das Gesicht, die Lippen oder die Zunge
• Rötung des Gesichts, des Halses, der Arme und gelegentlich der oberen Brust
• Unruhe
• Dinge sehen, hören oder fühlen, die nicht da sind
• Magenkrämpfe oder Schmerzen
• Durst
• Engegefühl in der Brust
• Konzentrationsschwierigkeiten
• Schlafstörungen
• ungewöhnliche Schläfrigkeit, Mattheit, Müdigkeit, Schwäche oder Trägheitsgefühl
• ungewöhnliche Müdigkeit oder Schwäche
• Erbrechen
• Gewichtsverlust

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Agitation
• Rückenschmerzen
• größere, erweiterte oder vergrößerte Pupillen (schwarzer Teil des Auges)
• verschwommene Sicht
• schwieriges oder gestörtes Atmen
• Gefühl von Wärme
• Fieber
• verstümmelte Rede
• erhöhte Lichtempfindlichkeit der Augen
• unregelmäßige, schnelle oder langsame oder flache Atmung
• Bewusstlosigkeit
• Stimmungsschwankungen oder mentale Veränderungen
• blasse oder blaue Lippen, Fingernägel oder Haut
• Anfälle
• Rede, die nicht verstanden wird
• steifer Hals
• ungewöhnliche Müdigkeit oder Schwäche

Some patients may also experience other side effects not listed. If you notice other side effects, contact your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Commonly used brand names

In the USA

• Lomocot
• Lomotil
• Lonox
• Vi-Atro

Available dosage forms:

• Tablette
• Lösung

Therapeutic class: Antidiarrheal

Pharmacological class: Atropine

Chemical Class: Diphenoxylate

More information