Viibryd titration package (oral)

Viibryd titration package (oral)

Oral route (tablet)

Antidepressants may increase the risk of suicidal thoughts and behavior in pediatric and young adult patients. Monitor patients of all ages closely for clinical deterioration and for the emergence of suicidal thoughts and behavior. Vilazodone hydrochloride is not approved for use in pediatric patients.

Used for the Viibryd titration package

This medicine is only available with a doctor's prescription.

Before using the Viibryd Titration Pack

When deciding whether to use a medicine, the risks of taking the medicine must be weighed against the benefits it produces. This is a decision that you and your doctor will make. The following should be noted with this medicine:

Allergies

Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also tell your doctor if you have other allergies, such as to foods, dyes, preservatives or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatrics

No appropriate studies have been conducted on the relationship between age and the effects of vilazodone in children and adolescents. Safety and effectiveness have not been established.

geriatrics

Studies conducted to date have not shown any geriatric-specific problems that would limit the benefit of vilazodone in the elderly. However, older patients are at higher risk of hyponatremia (low sodium in the blood) and age-related liver, kidney, or heart problems, which may require caution in patients receiving vilazodone.

Breastfeeding

There are insufficient studies in women to determine the risk to infants when using this drug while breast-feeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug interactions

Although certain medicines should not be used together at all, in other cases two different medicines can be used together, although interactions may occur. In these cases, your doctor may want to change the dose or other precautions may be necessary. If you are taking this medicine, it is particularly important that your doctor knows whether you are taking any of the medicines listed below. The following interactions were selected for their potential significance and are not necessarily exhaustive.

The use of this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or to change some of the other medications you are taking.

• Isocarboxazid
• Linezolid
• Methylenblau
• Metoclopramid
• Ozanimod
• Phenelzin
• Procarbazin
• Rasagilin
• Safinamid
• Selegilin
• Tranylcypromin

Using this medicine with any of the following medicines is not usually recommended but may be necessary in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both medicines.

• Abciximab
• Aceclofenac
• Acemetacin
• Acenocoumarol
• Alfentanil
• Almotriptan
• Amineptin
• Amitriptylin
• Amitriptylinoxid
• Amoxapin
• Amphetamin
• Amtolmetin Guacil
• Anagrelid
• Anileridin
• Apalutamid
• Apixaban
• Ardeparin
• Argatroban
• Aspirin
• Bemiparin
• Benzhydrocodon
• Benzphetamin
• Betrixaban
• Bivalirudin
• Boceprevir
• Bromfenac
• Brompheniramin
• Bufexamac
• Buprenorphin
• Buspiron
• Butorphanol
• Cangrelor
• Carbamazepin
• Celecoxib
• Ceritinib
• Certoparin
• Chlorpheniramin
• Cholinsalicylat
• Cilostazol
• Citalopram
• Clarithromycin
• Clomipramin
• Clonixin
• Clopidogrel
• Cobicistat
• Kokain
• Kodein
• Colchicin
• Conivaptan
• Cyclobenzaprin
• Cyclosporin
• Dabigatranetexilat
• Dalteparin
• Danaparoid
• Darunavir
• Desipramin
• Desirudin
• Desmopressin
• Desvenlafaxin
• Dexibuprofen
• Dexketoprofen
• Dextroamphetamin
• Dextromethorphan
• Dibenzepin
• Diclofenac
• Difenoxin
• Diflunisal
• Digoxin
• Dihydrocodein
• Diphenoxylat
• Dipyridamol
• Dipyron
• Dolasetron
• Doxepin
• Drotrecogin Alfa
• Droxicam
• Duloxetin
• Edoxaban
• Eletriptan
• Enoxaparin
• Enzalutamid
• Epoprostenol
• Eptifibatid
• Escitalopram
• Ethylmorphin
• Etodolac
• Etofenamat
• Etoricoxib
• Everolimus
• Felbinac
• Fenfluramin
• Fenoprofen
• Fentanyl
• Fepradinol
• Feprazon
• Floctafenin
• Flufenaminsäure
• Fluoxetin
• Flurbiprofen
• Fluvoxamin
• Fondaparinux
• Fosphenytoin
• Frovatriptan
• Gepiron
• Granisetron
• Heparin
• Hydrocodon
• Hydromorphon
• Hydroxyamphetamin
• Hydroxytryptophan
• Ibuprofen
• Idelalisib
• Iloprost
• Imipramin
• Indinavir
• Indomethacin
• Iobenguane I 131
• Itraconazol
• Ivosidenib
• Josamycin
• Ketobemidon
• Ketoconazol
• Ketoprofen
• Ketorolac
• Lasmiditan
• Lepirudin
• Levomilnacipran
• Levorphanol
• Lisdexamfetamin
• Lithium
• Lofepramin
• Lonafarnib
• Lopinavir
• Lorcaserin
• Lornoxicam
• Loxoprofen
• Lumacaftor
• Lumiracoxib
• Meclofenamat
• Mefenaminsäure
• Melitracen
• Meloxicam
• Meperidin
• Metaxalone
• Methadon
• Methamphetamin
• Methylphenidat
• Mibefradil
• Mifepriston
• Milnacipran
• Mirtazapin
• Mitotan
• Morniflumate
• Morphium
• Morphinsulfat-Liposom
• Nabumeton
• Nadroparin
• Nalbuphin
• Naproxen
• Naratriptan
• Nefazodon
• Nelfinavir
• Nepafenac
• Nicomorphin
• Nifluminsäure
• Nimesulid
• Nimesulid Beta Cyclodextrin
• Nortriptylin
• Ondansetron
• Opipramol
• Opium
• Opiumalkaloide
• Oxaprozin
• Oxycodon
• Oxymorphon
• Oxyphenbutazon
• Palonosetron
• Papaveretum
• Parecoxib
• Paregorisch
• Parnaparin
• Paroxetin
• Pentazocin
• Phenprocoumon
• Phenylbutazon
• Phenytoin
• Piketoprofen
• Piritramid
• Piroxicam
• Posaconazol
• Pranoprofen
• Prasugrel
• Proglumetacin
• Propyphenazon
• Proquazone
• Protein C
• Protriptylin
• Remifentanil
• Reviparin
• Ribociclib
• Rifampin
• Rifapentin
• Ritonavir
• Rivaroxaban
• Rizatriptan
• Rofecoxib
• Salicylsäure
• Salsalat
• Saquinavir
• Selexipag
• Sertralin
• Sibutramin
• Sirolimus
• Natriumsalicylat
• Johanniskraut
• Sufentanil
• Sulfinpyrazon
• Sulindac
• Sulodexid
• Sumatriptan
• Tacrolimus
• Tapentadol
• Telaprevir
• Telithromycin
• Tenoxicam
• Tianeptin
• Tiaprofensäure
• Ticagrelor
• Ticlopidin
• Tilidin
• Tinzaparin
• Tirofiban
• Tolfenaminsäure
• Tolmetin
• Tolvaptan
• Tramadol
• Trazodon
• Treprostinil
• Trimipramin
• Troleandomycin
• Tryptophan
• Tucatinib
• Valdecoxib
• Venlafaxin
• Vorapaxar
• Voriconazol
• Vortioxetin
• Warfarin
• Ziprasidon
• Zolmitriptan

Interactions with food/tobacco/alcohol

Certain medicines should not be taken during or near food or consumption of certain foods because interactions may occur. Consuming alcohol or tobacco with certain medications can also lead to interactions. The following interactions were selected for their potential significance and are not necessarily exhaustive.

The use of this medicine for any of the following conditions is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or frequency of use of this medication, or give you special instructions about food, alcohol, or tobacco consumption.

• Grapefruitsaft

Other medical problems

The presence of other medical problems may affect the use of this medicine. Be sure to tell your doctor if you have any other medical problems, especially:

• Bipolare Störung (Stimmungsstörung mit Manie und Depression) oder Risiko für oder
• Blutungsprobleme bzw
• Glaukom, Winkelblockglaukom oder
• Hyponatriämie (niedriger Natriumgehalt im Blut) oder
• Manie oder Hypomanie, Geschichte von oder
• Anfälle, Anamnese: Mit Vorsicht verwenden. Kann diese Bedingungen verschlimmern.

Proper use of the Viibryd Titration Pack

To improve your condition as much as possible, take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, or take it for longer than your doctor prescribed.

This medicine comes with a medication guide. It is very important that you read and understand this information. Be sure to ask your doctor if you don't understand anything.

It is best to take this medicine with food.

dosage

The dose of this medicine is different for different patients. Follow your doctor's instructions or the label directions. The following information includes average doses of this medicine only. If your dose is different, do not change it unless your doctor tells you to.

The amount of medicine you take depends on the strength of the medicine. In addition, the number of doses you take each day, the time between doses, and how long you take the medicine depend on the medical problem for which you are using the medicine.

• Für orale Darreichungsform (Tabletten):
  • Zur Behandlung von Depressionen:
    • Erwachsene – zunächst 10 Milligramm (mg) als Einzeldosis einmal täglich über 7 Tage. Anschließend kann Ihr Arzt Ihre Dosis je nach Bedarf anpassen. Allerdings beträgt die Dosis in der Regel nicht mehr als 40 mg pro Tag.
    • Kinder – Die Verwendung wird nicht empfohlen.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.

storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Protect from freezing.

Keep away from children.

Do not keep medications that are outdated or no longer needed.

Ask your doctor how to throw away medicines you don't use.

Precautions when using Viibryd Titration Pack

It is important that your doctor checks your progress at regular visits to allow changes to your dose and prevent unwanted side effects. Blood tests may be needed to check for adverse effects.

Do not take vilazodone with a monoamine oxidase (MAO) inhibitor (e.g., isocarboxazid [Marplan®], linezolid [Zyvox®] methylene blue injection, phenelzine [Nardil®], selegiline [Eldepryl®], or tranylcypromine [Parnate®]). Do not start taking vilazodone within two weeks of stopping an MAOI, and wait two weeks after stopping vilazodone before starting an MAOI. Taking them together or not waiting 2 weeks may cause confusion, agitation, agitation, stomach or intestinal distress, sudden high body temperature, extremely high blood pressure, or severe seizures.

Vilazodone may cause restlessness, irritability, or other abnormal behavior in some teenagers and young adults. It can also cause some people to have suicidal thoughts and tendencies or become more depressed. Some people may have trouble sleeping, become easily upset, have a large increase in energy, or begin to behave recklessly. If you or your caregiver notice any of these undesirable effects, tell your doctor immediately. Tell the doctor if you or anyone in your family has bipolar disorder (manic-depressive disorder) or has tried to commit suicide.

When vilazodone is taken with some medicines, a serious condition called serotonin syndrome may occur. Do not use vilazodone with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), lithium (Eskalith®, Lithobid®), tryptophan, St. John's wort, amphetamines, or some pain or migraine medications (e.g., meperidine, methadone). , Rizatriptan, Sumatriptan, Tramadol, Demerol®, Methadose®, Frova®, Imitrex®, Maxalt®, Relpax®, Ultram®. Consult your doctor first before taking other medicines with vilazodone.

This medicine may increase your risk of bleeding problems. Make sure your doctor knows if you are also taking other medicines that thin the blood, including aspirin, nonsteroidal anti-inflammatory drugs also called NSAIDs (e.g., diclofenac, ibuprofen, naproxen, Advil®, Aleve®, Celebrex®, Voltaren®), or warfarin (Coumadin®, Jantoven®).

Do not stop taking this medicine suddenly without consulting your doctor first. If you have been instructed to stop taking vilazodone, ask your doctor how to slowly reduce the dose. This reduces the risk of withdrawal symptoms such as dizziness, nausea, headaches, vomiting, increased sweating, irritability, nightmares, seizures, or pins and needles.

Hyponatremia (low levels of sodium in the blood) may occur with this medicine. This is more common in older patients, those taking diuretics for high blood pressure, or those whose amount of fluid in the body has decreased due to severe diarrhea or vomiting. Contact your doctor immediately if you experience confusion, difficulty concentrating, headaches, memory problems, weakness and unsteadiness.

Consumption of alcohol is not recommended in patients taking this medicine.

Vilazodone may cause dizziness or sleepiness in some people. Make sure you know how you react to this medicine before driving, operating machinery, or doing anything else that could be dangerous if you are dizzy or inattentive.

Consult your doctor immediately if you have lost interest in sexual intercourse, have delayed or inability to orgasm in women, are unable to have or maintain an erection in men, or have lost your sexual ability, desire, drive, or performance. These could be symptoms of sexual dysfunction.

Do not take any other medicines unless you have discussed this with your doctor. This includes both prescription and non-prescription (over-the-counter [OTC]) medicines and herbal (e.g. St. John's wort) or vitamin supplements.

Viibryd Titration Pack side effects

In addition to the necessary effects, a medicine may also have some undesirable effects. Although not all of these side effects may occur, medical attention may be required if they occur.

Consult your doctor immediately if any of the following side effects occur:

Less common

• Handlungen, die außer Kontrolle geraten
• Angst
• Brennen, Krabbeln, Jucken, Taubheitsgefühl, Kribbeln, Kribbeln oder Kribbeln
• Brustschmerzen oder Unwohlsein
• vermindertes Interesse am Geschlechtsverkehr
• verzögerter oder fehlender Orgasmus
• zusätzlicher Herzschlag
• schneller, unregelmäßiger, hämmernder oder rasender Herzschlag oder Puls
• Unfähigkeit, eine Erektion zu haben oder aufrechtzuerhalten
• Reizbarkeit
• Verlust der sexuellen Fähigkeiten, des Verlangens, des Antriebs oder der Leistung
• Zittern in den Beinen, Armen, Händen oder Füßen
• Schwitzen
• Mit Begeisterung reden, fühlen und handeln
• Zittern oder Zittern der Hände oder Füße

Some side effects may occur that usually do not require medical attention. These side effects may disappear during treatment as your body gets used to the medicine. Your doctor may also be able to give you ways to prevent or reduce some of these side effects. If any of the following side effects persist or are bothersome, or if you have any questions, contact your doctor:

More common

• Durchfall
• Schwindel
• trockener Mund
• Brechreiz
• Schlafstörungen

Less common

• Abnormale Träume
• Schmerzen oder Unwohlsein in den Unterschenkeln oder Krabbelgefühl in den Beinen
• saurer oder saurer Magen
• Aufstoßen
• Blindheit
• Völlegefühl oder Völlegefühl
• verschwommene Sicht
• Geschmacksveränderung
• verminderte Sehkraft
• Schwierigkeiten beim Bewegen
• Schläfrigkeit
• trockene Augen
• überschüssige Luft oder Gas im Magen oder Darm
• sich nervös fühlen
• Kopfschmerzen, stark und pochend
• Sodbrennen
• gesteigerter oder verminderter Appetit
• vermehrtes Schwitzen
• Verdauungsstörungen
• Appetitverlust
• Geschmacksverlust
• Muskelschmerzen oder -steifheit
• Nachtschweiß
• Schmerzen in den Gelenken
• Gas geben
• entspannt und ruhig
• Unruhe
• Schläfrigkeit oder ungewöhnliche Schläfrigkeit
• Magenschmerzen, Unwohlsein oder Unruhe
• ungewöhnliche Müdigkeit oder Schwäche
• Erbrechen
• Schwäche

Incident not known

• Nachlassender Geruch
• Augenschmerzen
• Verlust des Geruchssinns

Some patients may also experience other side effects not listed. If you notice other side effects, contact your doctor.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Commonly used brand names

In the USA

• Viibryd
• Viibryd-Titrationspaket

Available dosage forms:

• Tablette

Therapeutic class: Antidepressant

• Was sind einige häufige Nebenwirkungen von Antidepressiva?

More information