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New biomarker for Alzheimer's disease: Early warning sign discovered in brain activity
New evidence of early Alzheimer's warning signs discovered: Researchers find increased brain activity as a possible first symptom. Experts hope for better early detection and treatment.
New biomarker for Alzheimer's disease: Early warning sign discovered in brain activity
In order to detect Alzheimer's early, researchers are looking for signs that could indicate the onset of the disease. A recent study suggests that increased activity in specific parts of the brain may represent an early warning signal long before classic symptoms appear. Alzheimer's disease often remains undetected for a long time, which makes treatment difficult. Research is increasingly focusing on understanding the causes. A US research team discovered “biomarkers” for Alzheimer’s in an animal study.
Typical cognitive losses and memory gaps only appear later in the course of the disease. However, early signs, such as behavioral changes, indicate that Alzheimer's disease is on the horizon at an early stage. The latest findings could contribute to a better understanding of the disease, although they are not yet directly used in clinical practice.
Studies show that patients at high risk of Alzheimer's disease show an increase in brain activity in the early stages of the disease's development. An abnormality in neuronal activity could indicate that something is wrong in the brain. Experiments in mice showed that a particular protein (PSD-95) is associated with increased activity in neuronal connections and may be an early indicator of Alzheimer's disease.
Researchers see PSD-95 as potentially a new starting point for early detection and possible slowing of the progression of Alzheimer's disease. While these findings will take time to implement, they could represent an important step toward more targeted and effective treatment approaches.