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A higher McCance brain care score associated with a lower risk of stroke in women
Women with a higher McCance Brain Care Score (BCS) - a score that measures physical, lifestyle and social-emotional factors - have a lower risk of experiencing a stroke or other cerebrovascular event that reduces blood flow to the brain. The results are published in Neurology, medical journal of the American Academy of Neurology. Our results highlight that the McCance Brain Care Score is a valuable tool for predicting cerebrovascular event risk in women for whom stroke remains a leading cause of death. Our study further highlights the need for broader, long-term research in diverse populations and examines how changes in ratings versus lifespan affect the risk of stroke...
A higher McCance brain care score associated with a lower risk of stroke in women
Women with a higher McCance Brain Care Score (BCS) - a score that measures physical, lifestyle and social-emotional factors - have a lower risk of experiencing a stroke or other cerebrovascular event that reduces blood flow to the brain. The results will be published in Neurology, medical journal of the American Academy of Neurology.
Our results highlight that the McCance Brain Care Score is a valuable tool for predicting cerebrovascular event risk in women for whom stroke remains a leading cause of death. Our study further highlights the need for broader, long-term research in diverse populations examining how changes in ratings versus lifespan affect the risk of stroke and related events. “
Nirupama Yechoor, MD, MSC, senior author in the Department of Neurology at Massachusetts General Hospital
One in five women between the ages of 55 and 75 in the United States are expected to experience a stroke. Previous research has shown that the McCance Brain Care Score can predict the risk of stroke, dementia and depression in a general population. In the BCS, 12 modifiable risk factors range from 0 to 21 points, including physical components (blood pressure, blood sugar, cholesterol levels, and body mass index [BMI]), lifestyle factors (alcohol consumption, diet, smoking, physical activity, and sleep), and social-emotional factors (social relationships, stress, and sense of meaning in life).
Together with lead author Devanshi Choksi, MBBS, MPH, a research fellow in the Department of Neurology at MGH, Yechoor, and colleagues, the study resulted in data from 21,271 women with a mean age of 57.9 years. Using data collected from the WHS, investigators calculated women's BCS and used follow-up data to compare assessments and cerebrovascular event incidence.
They found that a higher score correlated with a reduced risk of cerebrovascular events over life. At an average follow-up of 22.4 years, 6.1 percent of participants had a cerebrovascular event (stroke or transient ischemic attack). Those with five points higher baseline BCs (the average baseline value of 15) were 37 percent less likely to have a cerebrovascular event after adjusting for age, menopausal status, use of hormonal replacement therapy and other cardiovascular disease risk factors.
Sources:
Choksi, D.,et al.(2025). Use of the Brain Care Score to Estimate the Risk of Incident Cerebrovascular Events in Middle-Aged Women. Neurology. doi.org/10.1212/wnl.0000000000213674.