To examine the role of repeat esophagogastroduodenoscopy and colonoscopy in the diagnosis of GI bleeding
Gastrointestinal (GI) bleeding is a common and potentially life-threatening condition that requires prompt and accurate diagnosis. Esophagogastroduodenoscopy (EGD) and colonoscopy are the primary diagnostic modalities, but initial investigations sometimes fail to identify the source of bleeding. In such cases, repeated endoscopic evaluations may improve detection rates. This review examines the role of repeat EGD and colonoscopy in the diagnosis of GI bleeding and highlights the conditions in which they are most beneficial and the challenges associated with their use. Incidence and causes of gastrointestinal bleeding GI bleeding is divided into upper, middle...
To examine the role of repeat esophagogastroduodenoscopy and colonoscopy in the diagnosis of GI bleeding
Gastrointestinal (GI) bleeding is a common and potentially life-threatening condition that requires prompt and accurate diagnosis. Esophagogastroduodenoscopy (EGD) and colonoscopy are the primary diagnostic modalities, but initial investigations sometimes fail to identify the source of bleeding. In such cases, repeated endoscopic evaluations may improve detection rates. This review examines the role of repeat EGD and colonoscopy in the diagnosis of GI bleeding and highlights the conditions in which they are most beneficial and the challenges associated with their use.
Incidence and causes of gastrointestinal bleeding
GI bleeds are classified into upper, middle, and lower GI bleeds based on the bleeding site. Acute upper GI bleeding has an incidence of 84 to 160 cases per 100,000 people per year, with a mortality rate of 10%. Peptic ulcers, variceal bleeding and mucosal erosions are among the most common causes. Lower GI bleeding, with an incidence of 20 to 33 cases per 100,000 people, is commonly caused by diverticular disease, hemorrhoids, malignancies, and colitis. The diagnostic accuracy of EGD for upper GI bleeding is approximately 90–95%, while colonoscopy has a diagnostic rate of 48–90% for lower GI bleeding.
Role of repeat EGD and colonoscopy
Certain conditions such as Dieulafoy's disease, intermittent bleeding, and limited visualization during the initial endoscopy may require repeat investigations. Repeated EGD has been shown to improve lesion detection, particularly in cases where the initial examination is inconclusive due to active bleeding or poor visualization. Similarly, repeat colonoscopy is valuable for detecting differential bleeding and assessing recurrent bleeding.
Indications for repeat endoscopy
Repeat EGD and colonoscopy should be considered in the following scenarios:
- Schlechte Visualisierung während der ersten Endoskopie – Blutgerinnsel, Lebensmittelreste oder unzureichende Darmvorbereitung können Läsionen verdecken.
- Unvollständige Erstuntersuchung – Wenn das erste Verfahren nicht die volle Visualisierung des GI -Trakts erreicht.
- Wiederkehrende oder anhaltende Blutungen – Klinischer Hinweise auf eine anhaltende Blutung können auf eine fehlende Läsion hinweisen.
- Zusätzliche Bildgebung deutet darauf hin, dass eine Blutungsquelle innerhalb der endoskopischen Reichweite aus der Kapselendoskopie oder der CT -Angiographie wiederholte Verfahren leiten kann.
Optimizing the utility of repeat endoscopy
To minimize the need for repeat procedures, proper bowel preparation, experienced endoscopists and advanced imaging modalities. Scheduling endoscopic examinations at appropriate times, particularly within 24 hours for high-risk patients, improves diagnostic yield. Emerging technologies, such as waterjet-assisted colonoscopy and capped endoscopy, are improving visualization and lesion detection rates.
Conclusions
Repeat EGD and colonoscopy play a crucial role in diagnosing GI bleeding when initial investigations do not identify the source of bleeding. While routine repeat procedures are not always necessary, careful selection of patients based on clinical factors can improve diagnostic accuracy and improve patient outcomes. Further research is needed to establish standardized guidelines for repeat endoscopy in GI bleeding management.
Sources:
Liu, T.,et al. (2024). Repeated Esophagogastroduodenoscopy and Colonoscopy in the Diagnosis of Gastrointestinal Bleeding. Journal of Translational Gastroenterology. doi.org/10.14218/jtg.2024.00024.